FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2544702933> ?p ?o ?g. }

• W2544702933 endingPage "121" @default.
• W2544702933 startingPage "110" @default.
• W2544702933 abstract "The understanding that adipocytes are greatly influenced by thermal changes combined with the advancement of non-invasive ultrasound technologies have led to the application of ultrasound as an energy source to induce thermal fat destruction. While application of high intensity focused, ultrasound energy have been widely explored, there is far less information regarding the effects of non-focused ultrasound on adipose tissue. The purpose of this study was to characterize the effects of a novel transcutaneous, multi-elements, non-focused ultrasound energy regimen in an animal model, as a proof-of-concept of its potential to treat non-invasive subcutaneous benign tumors.The non-invasive transcutaneous ultrasound system prototype (LUMENIS, Ltd., Yoqneam, Israel) was applied to thermally induce adipocytes' death. During treatment, the ultrasound energy was transmitted into the subcutaneous adipose tissue (SAT) of 12 domestic adult female pigs. Two modes of operation (long and short), which differ in both the acoustic energy applied to the tissue and in their time durations (i.e., differ in their power settings), were used in this study. Efficacy and safety assessments included: Temperature measurement of skin and subcutaneous adipose tissue (SAT) visual inspection and ultrasound imaging of the thermally affected areas, histopathological assessment of tissue samples using hematoxylin & eosin, and Masson's trichrome stains and in situ cell death detection kit for apoptosis assessment.The long and short treatment modes led to a 13.2°C and 17.8°C rise from baseline, respectively, in the SAT, whereas skin surface temperature was practically unaffected. Visual, ultrasonographic, and histopathological evaluation of the treated area showed SAT ablation. No treatment-related changes were observed in the epidermis, dermis subcutaneous muscle and nerves, or in livers and kidneys of treated animals. Additionally, no significant changes from baseline in blood- and urine-borne analytes were detected post-treatment.The novel transcutaneous, multi-elements, non-focused ultrasound energy regimen used in this study, proved effective in non-invasively ablating SAT in an animal model. The usage of low energy settings such as in the current study might reduce unwanted side effects related to high energy application. Lasers Surg. Med. 49:110-121, 2017. © 2016 Wiley Periodicals, Inc." @default.
• W2544702933 created "2016-11-04" @default.
• W2544702933 creator A5019202739 @default.
• W2544702933 creator A5075877164 @default.
• W2544702933 creator A5090595120 @default.
• W2544702933 date "2016-10-29" @default.
• W2544702933 modified "2023-09-24" @default.
• W2544702933 title "A novel transcutaneous, non-focused ultrasound energy delivering device is able to induce subcutaneous adipose tissue destruction in an animal model" @default.
• W2544702933 cites W1537062334 @default.
• W2544702933 cites W1980967279 @default.
• W2544702933 cites W1981018568 @default.
• W2544702933 cites W1982307958 @default.
• W2544702933 cites W2002431454 @default.
• W2544702933 cites W2004998372 @default.
• W2544702933 cites W2028405694 @default.
• W2544702933 cites W2048558161 @default.
• W2544702933 cites W2063206003 @default.
• W2544702933 cites W2063791846 @default.
• W2544702933 cites W2066854057 @default.
• W2544702933 cites W2067775316 @default.
• W2544702933 cites W2084289098 @default.
• W2544702933 cites W2089092965 @default.
• W2544702933 cites W2104377141 @default.
• W2544702933 cites W2125327375 @default.
• W2544702933 cites W2127746881 @default.
• W2544702933 cites W2129733029 @default.
• W2544702933 cites W2131258853 @default.
• W2544702933 cites W2160969869 @default.
• W2544702933 cites W2415752696 @default.
• W2544702933 cites W4233046774 @default.
• W2544702933 doi "https://doi.org/10.1002/lsm.22586" @default.
• W2544702933 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27794165" @default.
• W2544702933 hasPublicationYear "2016" @default.
• W2544702933 type Work @default.
• W2544702933 sameAs 2544702933 @default.
• W2544702933 citedByCount "2" @default.
• W2544702933 countsByYear W25447029332022 @default.
• W2544702933 countsByYear W25447029332023 @default.
• W2544702933 crossrefType "journal-article" @default.
• W2544702933 hasAuthorship W2544702933A5019202739 @default.
• W2544702933 hasAuthorship W2544702933A5075877164 @default.
• W2544702933 hasAuthorship W2544702933A5090595120 @default.
• W2544702933 hasConcept C125473707 @default.
• W2544702933 hasConcept C126322002 @default.
• W2544702933 hasConcept C126838900 @default.
• W2544702933 hasConcept C136229726 @default.
• W2544702933 hasConcept C142724271 @default.
• W2544702933 hasConcept C143753070 @default.
• W2544702933 hasConcept C171089720 @default.
• W2544702933 hasConcept C2776101711 @default.
• W2544702933 hasConcept C2777300098 @default.
• W2544702933 hasConcept C2779727089 @default.
• W2544702933 hasConcept C2985948822 @default.
• W2544702933 hasConcept C71924100 @default.
• W2544702933 hasConcept C74864618 @default.
• W2544702933 hasConceptScore W2544702933C125473707 @default.
• W2544702933 hasConceptScore W2544702933C126322002 @default.
• W2544702933 hasConceptScore W2544702933C126838900 @default.
• W2544702933 hasConceptScore W2544702933C136229726 @default.
• W2544702933 hasConceptScore W2544702933C142724271 @default.
• W2544702933 hasConceptScore W2544702933C143753070 @default.
• W2544702933 hasConceptScore W2544702933C171089720 @default.
• W2544702933 hasConceptScore W2544702933C2776101711 @default.
• W2544702933 hasConceptScore W2544702933C2777300098 @default.
• W2544702933 hasConceptScore W2544702933C2779727089 @default.
• W2544702933 hasConceptScore W2544702933C2985948822 @default.
• W2544702933 hasConceptScore W2544702933C71924100 @default.
• W2544702933 hasConceptScore W2544702933C74864618 @default.
• W2544702933 hasIssue "1" @default.
• W2544702933 hasLocation W25447029331 @default.
• W2544702933 hasLocation W25447029332 @default.
• W2544702933 hasOpenAccess W2544702933 @default.
• W2544702933 hasPrimaryLocation W25447029331 @default.
• W2544702933 hasRelatedWork W1159156495 @default.
• W2544702933 hasRelatedWork W1416425891 @default.
• W2544702933 hasRelatedWork W1465196638 @default.
• W2544702933 hasRelatedWork W1564058646 @default.
• W2544702933 hasRelatedWork W1966157180 @default.
• W2544702933 hasRelatedWork W2135477061 @default.
• W2544702933 hasRelatedWork W2544702933 @default.
• W2544702933 hasRelatedWork W2610150565 @default.
• W2544702933 hasRelatedWork W2889838560 @default.
• W2544702933 hasRelatedWork W962726873 @default.
• W2544702933 hasVolume "49" @default.
• W2544702933 isParatext "false" @default.
• W2544702933 isRetracted "false" @default.
• W2544702933 magId "2544702933" @default.
• W2544702933 workType "article" @default.