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• W2544959966 abstract "Objectifs. Decrire les aspects sociodemographiques, cliniques et etiologiques des dysthyroidies. Methodologie. Il s’agit d’une etude transversale descriptive retrospective concernant les patients suivis dans le service de medecine interne de l’Hopital National de Niamey pour hyperthyroidie ou hypothyroidie de janvier 2011 a decembre 2013. Les goitres euthyroidiens et cancers de la thyroide ont ete exclus. Les donnees analysees etaient sociodemographiques, diagnostiques et etiologiques. Resultats. 60 patients ont ete colliges incluant 49 cas d’hyperthyroidies (46 femmes d’âge moyen egal a 42 ans et 3 hommes d’âge moyen egal a 42 ans) et 11 cas d’hypothyroidies (8 femmes d’âge moyen egal a 38 ans et 3 hommes d’âge moyen egal a 42 ans). Les signes principaux cliniques retrouves dans les hyperthyroidies etaient les tremblements (78%), la tachycardie (76%) et l’amaigrissement (73%). Au cours des hypothyroidies, l’on a note essentiellement la bradycardie (820%), le myxœdeme (73%) et la prise de poids (730%). Le bilan paraclinique montrait les profils classiques d’hyperthyroidie et d’hypothyroidie peripheriques avec une elevation des anti RTSH dans les cas de Basedow et des anti TPO pour les cas de maladie de Hashimoto. Trois groupes etiologiques ont ete trouves dans les hyperthyroidies : les causes immunologiques, le goitre multi nodulaire toxique, le nodule toxique isole. Trois groupes etiologiques ont aussi ete trouves dans les hypothyroidies : les causes iatrogenes, immunologiques et le goitre endemique. Conclusion : les dysthyroidies touchent surtout els femmes. Les hyperthyroidies sont trois plus frequents que les hypothyroidies et le tableau clique est classique. Les causes sont surtout auto-immunes.ABSTRACTObjectives. To report sociodemorgraphic, clinical and etiological aspects of thyroid dysfunctions. Methods. This was a retrospective study of patients with hyperthyroidism or hypothyroidism from January 2011 to December 2013. Euthyroid goiters and thyroid cancers were not included. We focused on sociodemographic, clinical and etiological aspects. Results: 60 patients were collected with 49 cases of hyperthyroidism including 3 men (mean age 42 years) and 46 women (mean age 42 years) and 11 cases of hypothyroidism including 3 men (mean age: 42 years) and 8 women (mean age 38 years). Common clinical signs in hyperthyroidism were tremor ( 77 %) , tachycardia (76%) , weight loss ( 73%) and in hypothyroidism : bradycardia ( 82 %) , myxedema ( 73 %) and weight gain ( 73 %). The Blood tests showed the classic profiles of hyperthyroidism and hypothyroidism and elevated RTSH antibodies in Basedow’s disease and TPO antibodies in Hashimoto's disease. Three etiological groups were found in hyperthyroidism: immunological causes, toxic multi nodular goiter, isolated toxic nodule and 3 groups in hypothyroidism: iatrogenic causes, immunological and endemic goiter. Conclusion: Dysthyroidisms are more common in females and hyperthyroidism is three-time s more common than hypothyroidism; The main causes are autoimmune diseases." @default.
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• W2544959966 date "2016-10-17" @default.
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• W2544959966 title "Les Dysthyroïdies dans le Service de Médecine Interne de l’Hôpital National de Niamey – Niger" @default.
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