Matches in SemOpenAlex for { <https://semopenalex.org/work/W2545585722> ?p ?o ?g. }
- W2545585722 endingPage "343" @default.
- W2545585722 startingPage "337" @default.
- W2545585722 abstract "Early specific diagnosis and effective treatment of hepatocellular carcinoma (HCC) are crucial. Expression of membrane-associated heparan sulfate proteoglycan glypican-3 (GPC-3) was recently found to increase as part of the malignant transformation of hepatocytes, and this increase is especially marked in patients with hepatitis B virus (HBV) infection, periportal cancerous embolus, or extra-hepatic metastasis. According to data from basic and clinical studies, the oncofetal antigen GPC-3 is a highly specific diagnostic biomarker of HCC and an indicator of its prognosis, and GPC-3 is also a promising target molecule for HCC gene therapy since it may play a crucial role in cell proliferation, metastasis, and invasion and it may mediate oncogenesis and oncogenic signaling pathways. This review summarizes recent advances in the use of oncofetal antigen GPC-3 to diagnose HBV-related HCC, estimate its prognosis, and its targeted therapy." @default.
- W2545585722 created "2016-11-04" @default.
- W2545585722 creator A5007873838 @default.
- W2545585722 creator A5022986460 @default.
- W2545585722 creator A5029964155 @default.
- W2545585722 creator A5036495266 @default.
- W2545585722 creator A5048578676 @default.
- W2545585722 creator A5051497305 @default.
- W2545585722 date "2016-01-01" @default.
- W2545585722 modified "2023-10-16" @default.
- W2545585722 title "Advances in the study of oncofetal antigen glypican-3 expression in HBV-related hepatocellular carcinoma" @default.
- W2545585722 cites W1507435475 @default.
- W2545585722 cites W167023414 @default.
- W2545585722 cites W1880447615 @default.
- W2545585722 cites W1903755783 @default.
- W2545585722 cites W1904587896 @default.
- W2545585722 cites W1964404867 @default.
- W2545585722 cites W1971922918 @default.
- W2545585722 cites W1972875962 @default.
- W2545585722 cites W1982221837 @default.
- W2545585722 cites W1982878288 @default.
- W2545585722 cites W1985777811 @default.
- W2545585722 cites W1986536399 @default.
- W2545585722 cites W1993121603 @default.
- W2545585722 cites W1996755755 @default.
- W2545585722 cites W2000307707 @default.
- W2545585722 cites W2000743302 @default.
- W2545585722 cites W2002533120 @default.
- W2545585722 cites W2008181994 @default.
- W2545585722 cites W2012353860 @default.
- W2545585722 cites W2019777638 @default.
- W2545585722 cites W2027639018 @default.
- W2545585722 cites W2039484689 @default.
- W2545585722 cites W2046012719 @default.
- W2545585722 cites W2053686751 @default.
- W2545585722 cites W2059119905 @default.
- W2545585722 cites W2061374201 @default.
- W2545585722 cites W2061515929 @default.
- W2545585722 cites W2074189826 @default.
- W2545585722 cites W2075759998 @default.
- W2545585722 cites W2078592784 @default.
- W2545585722 cites W2079254150 @default.
- W2545585722 cites W2086081018 @default.
- W2545585722 cites W2091013003 @default.
- W2545585722 cites W2091425194 @default.
- W2545585722 cites W2092532409 @default.
- W2545585722 cites W2111522726 @default.
- W2545585722 cites W2116191527 @default.
- W2545585722 cites W2119452455 @default.
- W2545585722 cites W2125900063 @default.
- W2545585722 cites W2129802218 @default.
- W2545585722 cites W2144619904 @default.
- W2545585722 cites W2151305493 @default.
- W2545585722 cites W2151359000 @default.
- W2545585722 cites W2152166430 @default.
- W2545585722 cites W2170898604 @default.
- W2545585722 cites W2171380576 @default.
- W2545585722 cites W2174171693 @default.
- W2545585722 cites W2210612405 @default.
- W2545585722 cites W2234453634 @default.
- W2545585722 cites W2261598422 @default.
- W2545585722 cites W2272984102 @default.
- W2545585722 cites W2298134441 @default.
- W2545585722 cites W2315243012 @default.
- W2545585722 cites W2324266697 @default.
- W2545585722 cites W2409398911 @default.
- W2545585722 cites W2413113996 @default.
- W2545585722 cites W2413809012 @default.
- W2545585722 cites W4245403358 @default.
- W2545585722 cites W592456630 @default.
- W2545585722 cites W991562320 @default.
- W2545585722 doi "https://doi.org/10.5582/bst.2016.01176" @default.
- W2545585722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27795482" @default.
- W2545585722 hasPublicationYear "2016" @default.
- W2545585722 type Work @default.
- W2545585722 sameAs 2545585722 @default.
- W2545585722 citedByCount "14" @default.
- W2545585722 countsByYear W25455857222017 @default.
- W2545585722 countsByYear W25455857222018 @default.
- W2545585722 countsByYear W25455857222019 @default.
- W2545585722 countsByYear W25455857222020 @default.
- W2545585722 countsByYear W25455857222021 @default.
- W2545585722 countsByYear W25455857222022 @default.
- W2545585722 countsByYear W25455857222023 @default.
- W2545585722 crossrefType "journal-article" @default.
- W2545585722 hasAuthorship W2545585722A5007873838 @default.
- W2545585722 hasAuthorship W2545585722A5022986460 @default.
- W2545585722 hasAuthorship W2545585722A5029964155 @default.
- W2545585722 hasAuthorship W2545585722A5036495266 @default.
- W2545585722 hasAuthorship W2545585722A5048578676 @default.
- W2545585722 hasAuthorship W2545585722A5051497305 @default.
- W2545585722 hasBestOaLocation W25455857221 @default.
- W2545585722 hasConcept C121608353 @default.
- W2545585722 hasConcept C126322002 @default.
- W2545585722 hasConcept C142724271 @default.
- W2545585722 hasConcept C147483822 @default.
- W2545585722 hasConcept C203014093 @default.
- W2545585722 hasConcept C2522874641 @default.