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- W2546236120 abstract "The first highly enantioselective α-fluorination of 2-acyl imidazoles utilizing iridium catalysis has been accomplished. This transformation features mild conditions and a remarkably broad substrate scope, providing an efficient and highly enantioselective approach to obtain a wide range of fluorine-containing 2-acyl imidazoles which are found in a variety of bioactive compounds and prodrugs. A large scale synthesis has also been tested to demonstrate the potential utility of this fluorination method." @default.
- W2546236120 created "2016-11-04" @default.
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- W2546236120 date "2016-11-10" @default.
- W2546236120 modified "2023-10-07" @default.
- W2546236120 title "Catalytic Enantioselective α-Fluorination of 2-Acyl Imidazoles via Iridium Complexes" @default.
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- W2546236120 doi "https://doi.org/10.1002/asia.201601306" @default.
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