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- W2546240307 abstract "Pleurotus ostreatus (Jacq.Fr.) P. Kumm. and P. cystidiosus OK Miller are culinary-medicinal mushrooms grown worldwide. Our previous studies have reported the promising oral hypoglycaemic potential of P. ostreatus and P. cystidiosus in both normal and alloxan-induced diabetic rats as well as the anti-inflammatory activity of P. ostreatus.This study evaluates the effect of suspensions of freeze dried and powdered P. ostreatus and P. cystidiosus on the fasting and postprandial serum glucose levels in healthy volunteers at a dose of 50 mg/kg body weight, followed by a glucose load. Safety of the both mushrooms after long term consumption by healthy volunteers was also investigated. There was a significant fasting and postprandial serum glucose reduction in P. ostreatus or P. cystidiosus groups when compared with respective control groups (p<0.05). The percentage reduction in the fasting serum glucose levels for P. ostreatus and P. cystidiosus groups were 6.1% and 6.4% respectively and the postprandial serum glucose reductions were 16.4 % and 12.1 %. There were no significant differences in serum levels of liver enzymes, creatinine as well as estimated creatinine clearance before and after one month from the treatment. This indicated that the consumption of P. ostreatus and P. cystidiosus over a period of time did not cause any significant hepato cellular damage and detrimental effects in the renal system of the healthy volunteers. In conclusion, long-term consumption of P. ostreatus and P. cystidiosus appears to be effective as functional foods for glycaemic control." @default.
- W2546240307 created "2016-11-04" @default.
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- W2546240307 date "2014-01-01" @default.
- W2546240307 modified "2023-09-22" @default.
- W2546240307 title "EFFECT OF CULINARY MEDICINAL MUSHROOMS, PLEUROTUS OSTREATUS AND P. CYSTIDIOSUS ON FASTING AND POSTPRANDIAL GLYCAEMIA IN HEALTHY VOLUNTEERS" @default.
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