FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2546356639> ?p ?o ?g. }

• W2546356639 endingPage "1131" @default.
• W2546356639 startingPage "1124" @default.
• W2546356639 abstract "RNAs can begin to fold immediately as they emerge from RNA polymerase. During cotranscriptional folding, interactions between nascent RNAs and ligands are able to direct the formation of alternative RNA structures, a feature exploited by noncoding RNAs called riboswitches to make gene-regulatory decisions. Despite their importance, cotranscriptional folding pathways have yet to be uncovered with sufficient resolution to reveal how cotranscriptional folding governs RNA structure and function. To access cotranscriptional folding at nucleotide resolution, we extended selective 2'-hydroxyl acylation analyzed by primer-extension sequencing (SHAPE-seq) to measure structural information of nascent RNAs during transcription. Using cotranscriptional SHAPE-seq, we determined how the cotranscriptional folding pathway of the Bacillus cereus crcB fluoride riboswitch undergoes a ligand-dependent bifurcation that delays or promotes terminator formation via a series of coordinated structural transitions. Our results directly link cotranscriptional RNA folding to a genetic decision and establish a framework for cotranscriptional analysis of RNA structure at nucleotide resolution." @default.
• W2546356639 created "2016-11-04" @default.
• W2546356639 creator A5000628196 @default.
• W2546356639 creator A5018372696 @default.
• W2546356639 creator A5031409953 @default.
• W2546356639 creator A5037046194 @default.
• W2546356639 creator A5060183257 @default.
• W2546356639 date "2016-10-31" @default.
• W2546356639 modified "2023-10-13" @default.
• W2546356639 title "Cotranscriptional folding of a riboswitch at nucleotide resolution" @default.
• W2546356639 cites W1525178364 @default.
• W2546356639 cites W1562551320 @default.
• W2546356639 cites W1583063839 @default.
• W2546356639 cites W1975715632 @default.
• W2546356639 cites W1984684892 @default.
• W2546356639 cites W1985278607 @default.
• W2546356639 cites W1986067700 @default.
• W2546356639 cites W1992263711 @default.
• W2546356639 cites W2020375786 @default.
• W2546356639 cites W2033823752 @default.
• W2546356639 cites W2041053455 @default.
• W2546356639 cites W2043411229 @default.
• W2546356639 cites W2044410490 @default.
• W2546356639 cites W2054539464 @default.
• W2546356639 cites W2066444035 @default.
• W2546356639 cites W2067258168 @default.
• W2546356639 cites W2067947421 @default.
• W2546356639 cites W2068146975 @default.
• W2546356639 cites W2069475276 @default.
• W2546356639 cites W2070677411 @default.
• W2546356639 cites W2080251448 @default.
• W2546356639 cites W2088892367 @default.
• W2546356639 cites W2094507358 @default.
• W2546356639 cites W2096190151 @default.
• W2546356639 cites W2099378111 @default.
• W2546356639 cites W2125952821 @default.
• W2546356639 cites W2133014975 @default.
• W2546356639 cites W2133203832 @default.
• W2546356639 cites W2140139924 @default.
• W2546356639 cites W2141985609 @default.
• W2546356639 cites W2142673930 @default.
• W2546356639 cites W2148575508 @default.
• W2546356639 cites W23154420 @default.
• W2546356639 cites W2340426779 @default.
• W2546356639 cites W27390564 @default.
• W2546356639 doi "https://doi.org/10.1038/nsmb.3316" @default.
• W2546356639 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5497173" @default.
• W2546356639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27798597" @default.
• W2546356639 hasPublicationYear "2016" @default.
• W2546356639 type Work @default.
• W2546356639 sameAs 2546356639 @default.
• W2546356639 citedByCount "152" @default.
• W2546356639 countsByYear W25463566392017 @default.
• W2546356639 countsByYear W25463566392018 @default.
• W2546356639 countsByYear W25463566392019 @default.
• W2546356639 countsByYear W25463566392020 @default.
• W2546356639 countsByYear W25463566392021 @default.
• W2546356639 countsByYear W25463566392022 @default.
• W2546356639 countsByYear W25463566392023 @default.
• W2546356639 crossrefType "journal-article" @default.
• W2546356639 hasAuthorship W2546356639A5000628196 @default.
• W2546356639 hasAuthorship W2546356639A5018372696 @default.
• W2546356639 hasAuthorship W2546356639A5031409953 @default.
• W2546356639 hasAuthorship W2546356639A5037046194 @default.
• W2546356639 hasAuthorship W2546356639A5060183257 @default.
• W2546356639 hasBestOaLocation W25463566392 @default.
• W2546356639 hasConcept C104317684 @default.
• W2546356639 hasConcept C116403925 @default.
• W2546356639 hasConcept C121332964 @default.
• W2546356639 hasConcept C1276947 @default.
• W2546356639 hasConcept C148625055 @default.
• W2546356639 hasConcept C178046730 @default.
• W2546356639 hasConcept C185592680 @default.
• W2546356639 hasConcept C194993378 @default.
• W2546356639 hasConcept C2776441376 @default.
• W2546356639 hasConcept C2776449523 @default.
• W2546356639 hasConcept C2780048736 @default.
• W2546356639 hasConcept C42943712 @default.
• W2546356639 hasConcept C54355233 @default.
• W2546356639 hasConcept C547475151 @default.
• W2546356639 hasConcept C67705224 @default.
• W2546356639 hasConcept C70721500 @default.
• W2546356639 hasConcept C86803240 @default.
• W2546356639 hasConceptScore W2546356639C104317684 @default.
• W2546356639 hasConceptScore W2546356639C116403925 @default.
• W2546356639 hasConceptScore W2546356639C121332964 @default.
• W2546356639 hasConceptScore W2546356639C1276947 @default.
• W2546356639 hasConceptScore W2546356639C148625055 @default.
• W2546356639 hasConceptScore W2546356639C178046730 @default.
• W2546356639 hasConceptScore W2546356639C185592680 @default.
• W2546356639 hasConceptScore W2546356639C194993378 @default.
• W2546356639 hasConceptScore W2546356639C2776441376 @default.
• W2546356639 hasConceptScore W2546356639C2776449523 @default.
• W2546356639 hasConceptScore W2546356639C2780048736 @default.
• W2546356639 hasConceptScore W2546356639C42943712 @default.
• W2546356639 hasConceptScore W2546356639C54355233 @default.
• W2546356639 hasConceptScore W2546356639C547475151 @default.
• W2546356639 hasConceptScore W2546356639C67705224 @default.

• next