Matches in SemOpenAlex for { <https://semopenalex.org/work/W2546433137> ?p ?o ?g. }
- W2546433137 abstract "The cell cycle involves an ordered series of macromolecular events that lead to cell division and the production of two daughter cells, each containing chromosomes identical to those in the parental cell. Biochemical and genetic techniques, as well as recombinant DNA technology, have been employed in studies of the eukaryotic cell cycle. These studies revealed that cell replication is primarily controlled by regulating the timing of nuclear DNA replication and mitosis through some kinases such as cyclins and cyclin-dependent kinases (CDKs). In this chapter, we first present a systematic approach for quantitatively characterizing the transcriptional regulatory network (TRN) of 20 significant target genes in the yeast cell cycle. Then, a method using a Module Finding Algorithm (MOFA) is described to find transcriptional regulatory modules (TRMs) regulated by a common set of transcription factors in the TRN of the yeast cell cycle to respond to crosstalk between the cell cycle and other cellular processes, thus providing a better understanding of the regulation of complex expression program of the cell cycle." @default.
- W2546433137 created "2016-11-11" @default.
- W2546433137 creator A5001505881 @default.
- W2546433137 creator A5038219293 @default.
- W2546433137 date "2017-01-01" @default.
- W2546433137 modified "2023-10-17" @default.
- W2546433137 title "Big Cellular Mechanisms in the Cell Cycle by System Identification and Big Data Mining" @default.
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