Matches in SemOpenAlex for { <https://semopenalex.org/work/W2547174163> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2547174163 endingPage "55" @default.
- W2547174163 startingPage "49" @default.
- W2547174163 abstract "T cell immunoglobulin and mucin domain 3(TIM3) is a negative regulator of cellular immunity and it is highly expressed on CD8+T cells in persistent viral infection and cancer setting as report. However, how TIM3 expressed on CD8+T cells in myelodysplastic syndrome (MDS), that is a malignant disorder, has not been clarified. Here, decreased CD8+T cells, less IFN-γ secretion in CD8+T cells and increased TIM3 on CD8+T cells had been seen. Increased TIM3+CD8+T cells with lower perforin and granzyme B expression and higher CD95 expression in MDS patients had been observed. These findings suggested that TIM3 might be related to CD8+T cells defect. Therefore, further explorations about mechanism of TIM3+CD8+T cells defect are needed, which might be helpful for adoptive T-cell therapy in MDS." @default.
- W2547174163 created "2016-11-11" @default.
- W2547174163 creator A5005244586 @default.
- W2547174163 creator A5006486369 @default.
- W2547174163 creator A5034185369 @default.
- W2547174163 creator A5064204355 @default.
- W2547174163 creator A5082426024 @default.
- W2547174163 creator A5083636205 @default.
- W2547174163 date "2016-12-01" @default.
- W2547174163 modified "2023-10-17" @default.
- W2547174163 title "Increased TIM3+CD8+T cells in Myelodysplastic Syndrome patients displayed less perforin and granzyme B secretion and higher CD95 expression" @default.
- W2547174163 cites W1971873029 @default.
- W2547174163 cites W1976105607 @default.
- W2547174163 cites W1991890073 @default.
- W2547174163 cites W1997731331 @default.
- W2547174163 cites W1998248903 @default.
- W2547174163 cites W2001479776 @default.
- W2547174163 cites W2032560191 @default.
- W2547174163 cites W2046234524 @default.
- W2547174163 cites W2076435885 @default.
- W2547174163 cites W2089202428 @default.
- W2547174163 cites W2108158604 @default.
- W2547174163 cites W2116317906 @default.
- W2547174163 cites W2130011407 @default.
- W2547174163 cites W2130338247 @default.
- W2547174163 cites W2157342679 @default.
- W2547174163 cites W2329974159 @default.
- W2547174163 doi "https://doi.org/10.1016/j.leukres.2016.11.003" @default.
- W2547174163 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27846431" @default.
- W2547174163 hasPublicationYear "2016" @default.
- W2547174163 type Work @default.
- W2547174163 sameAs 2547174163 @default.
- W2547174163 citedByCount "12" @default.
- W2547174163 countsByYear W25471741632019 @default.
- W2547174163 countsByYear W25471741632020 @default.
- W2547174163 countsByYear W25471741632021 @default.
- W2547174163 countsByYear W25471741632022 @default.
- W2547174163 countsByYear W25471741632023 @default.
- W2547174163 crossrefType "journal-article" @default.
- W2547174163 hasAuthorship W2547174163A5005244586 @default.
- W2547174163 hasAuthorship W2547174163A5006486369 @default.
- W2547174163 hasAuthorship W2547174163A5034185369 @default.
- W2547174163 hasAuthorship W2547174163A5064204355 @default.
- W2547174163 hasAuthorship W2547174163A5082426024 @default.
- W2547174163 hasAuthorship W2547174163A5083636205 @default.
- W2547174163 hasConcept C129374314 @default.
- W2547174163 hasConcept C154317977 @default.
- W2547174163 hasConcept C167672396 @default.
- W2547174163 hasConcept C183193105 @default.
- W2547174163 hasConcept C202751555 @default.
- W2547174163 hasConcept C203014093 @default.
- W2547174163 hasConcept C2776062744 @default.
- W2547174163 hasConcept C2779968557 @default.
- W2547174163 hasConcept C2780380082 @default.
- W2547174163 hasConcept C502942594 @default.
- W2547174163 hasConcept C55493867 @default.
- W2547174163 hasConcept C71924100 @default.
- W2547174163 hasConcept C86803240 @default.
- W2547174163 hasConcept C8891405 @default.
- W2547174163 hasConceptScore W2547174163C129374314 @default.
- W2547174163 hasConceptScore W2547174163C154317977 @default.
- W2547174163 hasConceptScore W2547174163C167672396 @default.
- W2547174163 hasConceptScore W2547174163C183193105 @default.
- W2547174163 hasConceptScore W2547174163C202751555 @default.
- W2547174163 hasConceptScore W2547174163C203014093 @default.
- W2547174163 hasConceptScore W2547174163C2776062744 @default.
- W2547174163 hasConceptScore W2547174163C2779968557 @default.
- W2547174163 hasConceptScore W2547174163C2780380082 @default.
- W2547174163 hasConceptScore W2547174163C502942594 @default.
- W2547174163 hasConceptScore W2547174163C55493867 @default.
- W2547174163 hasConceptScore W2547174163C71924100 @default.
- W2547174163 hasConceptScore W2547174163C86803240 @default.
- W2547174163 hasConceptScore W2547174163C8891405 @default.
- W2547174163 hasFunder F4320321001 @default.
- W2547174163 hasLocation W25471741631 @default.
- W2547174163 hasLocation W25471741632 @default.
- W2547174163 hasOpenAccess W2547174163 @default.
- W2547174163 hasPrimaryLocation W25471741631 @default.
- W2547174163 hasRelatedWork W1969504080 @default.
- W2547174163 hasRelatedWork W1980557243 @default.
- W2547174163 hasRelatedWork W2042623890 @default.
- W2547174163 hasRelatedWork W2048773810 @default.
- W2547174163 hasRelatedWork W2130431539 @default.
- W2547174163 hasRelatedWork W2565012256 @default.
- W2547174163 hasRelatedWork W2884205201 @default.
- W2547174163 hasRelatedWork W2991630458 @default.
- W2547174163 hasRelatedWork W3122126102 @default.
- W2547174163 hasRelatedWork W3159185942 @default.
- W2547174163 hasVolume "51" @default.
- W2547174163 isParatext "false" @default.
- W2547174163 isRetracted "false" @default.
- W2547174163 magId "2547174163" @default.
- W2547174163 workType "article" @default.