Matches in SemOpenAlex for { <https://semopenalex.org/work/W2547658293> ?p ?o ?g. }
- W2547658293 abstract "To assessed the sensitivity of human Burkitt’s lymphoma cells to rituximab and tositumomab at differential levels of CD20 molecules on cell surface. Cells that possess low CD20 levels exposed with γ-radiation and thereafter treated with mAbs. During present investigation we found that cells treated post irradiation showed higher levels of cell death. Moreover, tositumumab found to be strong cell death inducer. In addition, Bax / Bcl-2 ratio were also found higher in associated with differentiallevels of CD20 expressed cells as well as significant inhibition of pro-survival signaling such NF-κB and Akt pathways. These findings demonstrated that the efficacy of anti-CD20 mAbs is dependent on the surface levels of CD20. Based on these results, we hypothesized that irradiation just prior to immunotherapy may provide new treatment options even in aggressive B-cell lymphoma, which are having low levels CD20 or even resistant to current therapies in vivo." @default.
- W2547658293 created "2016-11-11" @default.
- W2547658293 creator A5000322586 @default.
- W2547658293 creator A5004608187 @default.
- W2547658293 creator A5029931151 @default.
- W2547658293 creator A5031189242 @default.
- W2547658293 date "2015-01-01" @default.
- W2547658293 modified "2023-09-23" @default.
- W2547658293 title "INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES (Int. J. of Pharm. Life Sci.) Differential levels of CD20 play crucial role in response of antibody mediated cell death in Burkitt's Lymphoma Cell Line 'Daudi'" @default.
- W2547658293 cites W1484629663 @default.
- W2547658293 cites W1682849199 @default.
- W2547658293 cites W1854005499 @default.
- W2547658293 cites W1915689252 @default.
- W2547658293 cites W1964617786 @default.
- W2547658293 cites W1964840052 @default.
- W2547658293 cites W1969690844 @default.
- W2547658293 cites W1972609102 @default.
- W2547658293 cites W1973634732 @default.
- W2547658293 cites W1986568749 @default.
- W2547658293 cites W2009109361 @default.
- W2547658293 cites W2009512645 @default.
- W2547658293 cites W2022588086 @default.
- W2547658293 cites W2027374210 @default.
- W2547658293 cites W2036982580 @default.
- W2547658293 cites W2039019317 @default.
- W2547658293 cites W2045862009 @default.
- W2547658293 cites W2056473947 @default.
- W2547658293 cites W2057796652 @default.
- W2547658293 cites W2057858743 @default.
- W2547658293 cites W2069524809 @default.
- W2547658293 cites W2074262644 @default.
- W2547658293 cites W2079756029 @default.
- W2547658293 cites W2100246815 @default.
- W2547658293 cites W2101297848 @default.
- W2547658293 cites W2128635872 @default.
- W2547658293 cites W2129041705 @default.
- W2547658293 cites W2133190342 @default.
- W2547658293 cites W2134677113 @default.
- W2547658293 cites W2146629016 @default.
- W2547658293 cites W2148766690 @default.
- W2547658293 cites W2159650080 @default.
- W2547658293 cites W2164073959 @default.
- W2547658293 cites W51278734 @default.
- W2547658293 cites W1976893845 @default.
- W2547658293 hasPublicationYear "2015" @default.
- W2547658293 type Work @default.
- W2547658293 sameAs 2547658293 @default.
- W2547658293 citedByCount "0" @default.
- W2547658293 crossrefType "journal-article" @default.
- W2547658293 hasAuthorship W2547658293A5000322586 @default.
- W2547658293 hasAuthorship W2547658293A5004608187 @default.
- W2547658293 hasAuthorship W2547658293A5029931151 @default.
- W2547658293 hasAuthorship W2547658293A5031189242 @default.
- W2547658293 hasConcept C18031839 @default.
- W2547658293 hasConcept C190283241 @default.
- W2547658293 hasConcept C203014093 @default.
- W2547658293 hasConcept C2779338263 @default.
- W2547658293 hasConcept C2780653079 @default.
- W2547658293 hasConcept C31573885 @default.
- W2547658293 hasConcept C502942594 @default.
- W2547658293 hasConcept C54355233 @default.
- W2547658293 hasConcept C55493867 @default.
- W2547658293 hasConcept C71924100 @default.
- W2547658293 hasConcept C81885089 @default.
- W2547658293 hasConcept C86803240 @default.
- W2547658293 hasConceptScore W2547658293C18031839 @default.
- W2547658293 hasConceptScore W2547658293C190283241 @default.
- W2547658293 hasConceptScore W2547658293C203014093 @default.
- W2547658293 hasConceptScore W2547658293C2779338263 @default.
- W2547658293 hasConceptScore W2547658293C2780653079 @default.
- W2547658293 hasConceptScore W2547658293C31573885 @default.
- W2547658293 hasConceptScore W2547658293C502942594 @default.
- W2547658293 hasConceptScore W2547658293C54355233 @default.
- W2547658293 hasConceptScore W2547658293C55493867 @default.
- W2547658293 hasConceptScore W2547658293C71924100 @default.
- W2547658293 hasConceptScore W2547658293C81885089 @default.
- W2547658293 hasConceptScore W2547658293C86803240 @default.
- W2547658293 hasLocation W25476582931 @default.
- W2547658293 hasOpenAccess W2547658293 @default.
- W2547658293 hasPrimaryLocation W25476582931 @default.
- W2547658293 hasRelatedWork W2028971492 @default.
- W2547658293 hasRelatedWork W2092853448 @default.
- W2547658293 hasRelatedWork W2108999808 @default.
- W2547658293 hasRelatedWork W2172473781 @default.
- W2547658293 hasRelatedWork W2261122747 @default.
- W2547658293 hasRelatedWork W2553044056 @default.
- W2547658293 hasRelatedWork W2557647391 @default.
- W2547658293 hasRelatedWork W2559935001 @default.
- W2547658293 hasRelatedWork W2566143231 @default.
- W2547658293 hasRelatedWork W2585484723 @default.
- W2547658293 hasRelatedWork W2585667305 @default.
- W2547658293 hasRelatedWork W2593277776 @default.
- W2547658293 hasRelatedWork W2979454343 @default.
- W2547658293 hasRelatedWork W2987995583 @default.
- W2547658293 hasRelatedWork W2990269919 @default.
- W2547658293 hasRelatedWork W3016012028 @default.
- W2547658293 hasRelatedWork W3096283091 @default.
- W2547658293 hasRelatedWork W3099378539 @default.
- W2547658293 hasRelatedWork W3174466897 @default.
- W2547658293 hasRelatedWork W3184415634 @default.