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- W2547819377 abstract "One new chromone 3,3-dimethylallylspatheliachromene methyl ether (1), as well as five known chromones, 6-(3-methylbut-2-enyl) allopteroxylin methyl ether (2), 6-(3-methylbut-2-enyl) allopteroxylin (3), 3,3-dimethylallylspatheliachromene (4), 5-O-methylcneorumchromone K (5) and spatheliabischromene (6), two alkaloids, 8-methoxy-N-methylflindersine (7) and 8-methoxyflindersine (8), and two limonoids, limonin diosphenol (9) and rutaevin (10), were isolated from Dictyoloma vandellianum A. Juss (Rutaceae). Cytotoxic activities towards tumor cell lines B16-F10, HepG2, K562 and HL60 and non-tumor cells PBMC were evaluated for compounds 1 – 6. Compound 1 was the most active showing IC50 values ranging from 6.26 to 14.82 μg/ml in B16-F10 and K562 cell lines, respectively, and presented IC50 value of 11.65 μg/ml in PBMC cell line." @default.
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- W2547819377 date "2017-02-16" @default.
- W2547819377 modified "2023-10-16" @default.
- W2547819377 title "Pyranochromones from<i>Dictyoloma vandellianum</i>A.<scp>Juss</scp>and Their Cytotoxic Evaluation" @default.
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- W2547819377 doi "https://doi.org/10.1002/cbdv.201600276" @default.
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