Matches in SemOpenAlex for { <https://semopenalex.org/work/W2547936235> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2547936235 endingPage "bcr2016216720" @default.
- W2547936235 startingPage "bcr2016216720" @default.
- W2547936235 abstract "A man aged 33 years, born in Nepal, but resident in the UK for 7 years presented to the emergency department with a 4-day history of general malaise, fever (temperature 38.6°C) and a non-productive cough. His medical history was unremarkable and no high-risk behaviour was identified. Clinical examination confirmed decreased air entry bilaterally with bibasal crackles. He was tachycardic, with a heart rate of 120 bpm. Further investigation with a 12-lead ECG confirmed supraventricular tachycardia (SVT) which was terminated with vagal manoeuvres. His chest radiograph demonstrated left basal consolidation. His white cell count was 11×109/L and his C reactive protein was 43.2 mg/L. His blood cultures revealed no growth. He was diagnosed with community-acquired pneumonia and started treatment with amoxicillin and clarithromycin. 3 days post admission, he was intubated for 24 hours in the Department of Intensive Care Medicine. Further episodes of SVT were observed and an ECHO showed a severely dilated and impaired left ventricle. Further chest radiographs illustrated diffuse consolidation with evidence of pulmonary oedema. HIV serology was negative. He developed transaminitis and thrombocytopenia. An ultrasound scan of his liver showed no obvious liver pathology. He remained tachypnoeic and due to worsening pulmonary oedema and extensive consolidation, he was readmitted to the intensive care unit. A CT abdomen with contrast showed an unusual pattern of lymphadenopathy with disproportionately enlarged coeliac axis nodes (5×7×5 cm) and minor para-aortic adenopathy, suspicious for lymphoma. On inserting his central venous catheter in his right internal jugular vein, pus was inadvertently aspirated from his right neck. Acid alcohol fast bacilli (AAFFB) were isolated from the pus and was subsequently identified as Mycobacterium tuberculosis He started treatment with antitubercular medication rifater: a combination of rifampicin 720 mg od, isoniazid 300 mg po od and pyrazinamide 1750 mg. In addition, he received ethambutol 1000 mg po od and pyridoxine 5 mg. He developed worsening metabolic acidosis, pH 7.19, loss of respiratory compensation and pancytopenia. Right heart strain was evident on his Focused Intensive Care Echo. He developed an increased oxygen requirement and respiratory distress on the ventilator. An erect chest radiograph showed bilateral pneumothoraces and bronchopleural fistulae. A chest drain was inserted. Following discussion with the Cardiothoracic Surgeons, pleurodesis was not deemed possible. He developed inotropic-dependent shock with worsening lung compliance. As a result of his deteriorating ventilation, acidosis and hyperkalaemia, he started treatment with continuous veno-venous haemofiltration. With a diagnosis of miliary tuberculosis and SVT causing cardiogenic pulmonary oedema, this man sadly died with his family at his bedside 10 weeks following initial hospital presentation." @default.
- W2547936235 created "2016-11-11" @default.
- W2547936235 creator A5049333141 @default.
- W2547936235 creator A5051067001 @default.
- W2547936235 creator A5057963270 @default.
- W2547936235 date "2016-11-02" @default.
- W2547936235 modified "2023-10-16" @default.
- W2547936235 title "Miliary tuberculosis in an immunocompetent male with a fatal outcome" @default.
- W2547936235 cites W1571818011 @default.
- W2547936235 cites W1853967939 @default.
- W2547936235 cites W1971707830 @default.
- W2547936235 cites W1972659935 @default.
- W2547936235 cites W1990893737 @default.
- W2547936235 cites W2052486464 @default.
- W2547936235 cites W2073160461 @default.
- W2547936235 cites W2104497055 @default.
- W2547936235 cites W2108315712 @default.
- W2547936235 cites W2123643891 @default.
- W2547936235 cites W2124004982 @default.
- W2547936235 cites W2156771418 @default.
- W2547936235 cites W2157780090 @default.
- W2547936235 cites W2160275853 @default.
- W2547936235 cites W2167215889 @default.
- W2547936235 cites W2201373991 @default.
- W2547936235 cites W2274460208 @default.
- W2547936235 cites W2400075779 @default.
- W2547936235 doi "https://doi.org/10.1136/bcr-2016-216720" @default.
- W2547936235 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5129105" @default.
- W2547936235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27807020" @default.
- W2547936235 hasPublicationYear "2016" @default.
- W2547936235 type Work @default.
- W2547936235 sameAs 2547936235 @default.
- W2547936235 citedByCount "1" @default.
- W2547936235 countsByYear W25479362352021 @default.
- W2547936235 crossrefType "journal-article" @default.
- W2547936235 hasAuthorship W2547936235A5049333141 @default.
- W2547936235 hasAuthorship W2547936235A5051067001 @default.
- W2547936235 hasAuthorship W2547936235A5057963270 @default.
- W2547936235 hasBestOaLocation W25479362352 @default.
- W2547936235 hasConcept C118552586 @default.
- W2547936235 hasConcept C126322002 @default.
- W2547936235 hasConcept C126838900 @default.
- W2547936235 hasConcept C141071460 @default.
- W2547936235 hasConcept C177713679 @default.
- W2547936235 hasConcept C2776102371 @default.
- W2547936235 hasConcept C2776376669 @default.
- W2547936235 hasConcept C2777714996 @default.
- W2547936235 hasConcept C2777914695 @default.
- W2547936235 hasConcept C2780505380 @default.
- W2547936235 hasConcept C2780724011 @default.
- W2547936235 hasConcept C2780908675 @default.
- W2547936235 hasConcept C2781137159 @default.
- W2547936235 hasConcept C2987404301 @default.
- W2547936235 hasConcept C527108885 @default.
- W2547936235 hasConcept C71924100 @default.
- W2547936235 hasConceptScore W2547936235C118552586 @default.
- W2547936235 hasConceptScore W2547936235C126322002 @default.
- W2547936235 hasConceptScore W2547936235C126838900 @default.
- W2547936235 hasConceptScore W2547936235C141071460 @default.
- W2547936235 hasConceptScore W2547936235C177713679 @default.
- W2547936235 hasConceptScore W2547936235C2776102371 @default.
- W2547936235 hasConceptScore W2547936235C2776376669 @default.
- W2547936235 hasConceptScore W2547936235C2777714996 @default.
- W2547936235 hasConceptScore W2547936235C2777914695 @default.
- W2547936235 hasConceptScore W2547936235C2780505380 @default.
- W2547936235 hasConceptScore W2547936235C2780724011 @default.
- W2547936235 hasConceptScore W2547936235C2780908675 @default.
- W2547936235 hasConceptScore W2547936235C2781137159 @default.
- W2547936235 hasConceptScore W2547936235C2987404301 @default.
- W2547936235 hasConceptScore W2547936235C527108885 @default.
- W2547936235 hasConceptScore W2547936235C71924100 @default.
- W2547936235 hasLocation W25479362351 @default.
- W2547936235 hasLocation W25479362352 @default.
- W2547936235 hasLocation W25479362353 @default.
- W2547936235 hasLocation W25479362354 @default.
- W2547936235 hasOpenAccess W2547936235 @default.
- W2547936235 hasPrimaryLocation W25479362351 @default.
- W2547936235 hasRelatedWork W2030177610 @default.
- W2547936235 hasRelatedWork W2086786829 @default.
- W2547936235 hasRelatedWork W2135212189 @default.
- W2547936235 hasRelatedWork W2137514241 @default.
- W2547936235 hasRelatedWork W2234083531 @default.
- W2547936235 hasRelatedWork W2397209762 @default.
- W2547936235 hasRelatedWork W2415186040 @default.
- W2547936235 hasRelatedWork W2758265726 @default.
- W2547936235 hasRelatedWork W1929416573 @default.
- W2547936235 hasRelatedWork W2042092333 @default.
- W2547936235 isParatext "false" @default.
- W2547936235 isRetracted "false" @default.
- W2547936235 magId "2547936235" @default.
- W2547936235 workType "article" @default.