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• W2548448204 abstract "Future OncologyVol. 13, No. 2 EditorialFrom bench to operating theater: has the time come for a molecular scalpel?George Vartholomatos, George A Alexiou, Georgios D Lianos & Athanasios P KyritsisGeorge Vartholomatos Haematology Laboratory-Unit of Molecular Biology, University of Ioannina School of Medicine, 45110, Ioannina, GreeceSearch for more papers by this author, George A Alexiou*Author for correspondence: E-mail Address: alexiougrg@yahoo.gr Neurosurgical Institute, University of Ioannina School of Medicine, 45110, Ioannina, GreeceSearch for more papers by this author, Georgios D Lianos Neurosurgical Institute, University of Ioannina School of Medicine, 45110, Ioannina, GreeceSearch for more papers by this author & Athanasios P Kyritsis Neurosurgical Institute, University of Ioannina School of Medicine, 45110, Ioannina, GreeceSearch for more papers by this authorPublished Online:4 Nov 2016https://doi.org/10.2217/fon-2016-0413AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: flow cytometryintraoperative cell cycle analysessurgical marginssurgical oncologyReferences1 Swinney C, Li A, Bhatti I, Veeravagu A. Optimization of tumor resection with intra-operative magnetic resonance imaging. J. Clin. Neurosci. doi:10.1016/j.jocn.2016.05.030 (2016) (Epub ahead of print).Crossref, Medline, Google Scholar2 Hauser SB, Kockro RA, Actor B, Sarnthein J, Bernays RL. Combining 5-aminolevulinic acid fluorescence and intraoperative magnetic resonance imaging in glioblastoma surgery: a histology-based evaluation. Neurosurgery 78(4), 475–483 (2016).Crossref, Medline, Google Scholar3 Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ. ALA-Glioma Study Group. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre Phase III trial. Lancet Oncol. 7(5), 392–401 (2006).Crossref, Medline, CAS, Google Scholar4 Widhalm G, Kiesel B, Woehrer A et al. 5-Aminolevulinic acid induced fluorescence is a powerful intraoperative marker for precise histopathological grading of gliomas with non-significant contrast-enhancement. PLoS ONE 8(10), e76988 (2013).Crossref, Medline, CAS, Google Scholar5 Jarmusch AK, Pirro V, Baird Z, Hattab EM, Cohen-Gadol AA, Cooks RG. Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS. Proc. Natl Acad. Sci. USA 113(6), 1486–1491 (2016).Crossref, Medline, CAS, Google Scholar6 Balog J, Sasi-Szabó L, Kinross J et al. Intraoperative tissue identification using rapid evaporative ionization mass spectrometry. Sci. Transl. Med. 5(194), 194ra93 (2013).Crossref, Medline, Google Scholar7 Ifa DR, Eberlin LS. Ambient ionization mass spectrometry for cancer diagnosis and surgical margin evaluation. Clin. Chem. 62(1), 111–123 (2016).Crossref, Medline, CAS, Google Scholar8 Vartholomatos G, Alexiou G, Batistatou A, Kyritsis AP. Intraoperative cell-cycle analysis to guide brain tumor removal. Proc. Natl Acad. Sci. USA 111(36), E3755 (2014).Crossref, Medline, CAS, Google Scholar9 Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 144(5), 646–674 (2011).Crossref, Medline, CAS, Google Scholar10 Alexiou GA, Vartholomatos G, Goussia A et al. Fast cell cycle analysis for intraoperative characterization of brain tumor margins and malignancy. J. Clin. Neurosci. 22(1), 129–132 (2015).Crossref, Medline, Google Scholar11 Alexiou GA, Vartholomatos G, Stefanaki K et al. The role of fast cell cycle analysis in pediatric brain tumors. Pediatr. Neurosurg. 50(5), 257–263 (2015).Crossref, Medline, Google Scholar12 Giesen C, Wang HA, Schapiro D et al. Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry. Nat. Methods 11(4), 417–422 (2014).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByIntraoperative Flow Cytometry in Pediatric Brain Tumors1 January 2022The Past, Present and Future of Flow Cytometry in Central Nervous System Malignancies26 January 2021 | Methods and Protocols, Vol. 4, No. 1The emerging role of intraoperative flow cytometry in intracranial tumor surgeryClinical Neurology and Neurosurgery, Vol. 192Intraoperative cell cycle analysis for tumor margins evaluation: The future is now?International Journal of Surgery, Vol. 53Effectiveness of flow cytometry for brain tumor excisionPhotodiagnosis and Photodynamic Therapy, Vol. 18 Vol. 13, No. 2 eToC Sign up Follow us on social media for the latest updates Metrics Downloaded 40 times History Published online 4 November 2016 Published in print January 2017 Information© Future Medicine LtdKeywordsflow cytometryintraoperative cell cycle analysessurgical marginssurgical oncologyFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download" @default.
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