FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2548492968> ?p ?o ?g. }

• W2548492968 endingPage "478" @default.
• W2548492968 startingPage "469" @default.
• W2548492968 abstract "Body-on-a-chip systems replicate the size relationships of organs, blood distribution and blood flow, in accordance with human physiology. When operated with tissues derived from human cell sources, these systems are capable of simulating human metabolism, including the conversion of a prodrug to its effective metabolite, as well as its subsequent therapeutic actions and toxic side-effects. The system also permits the measurement of human tissue electrical and mechanical reactions, which provide a measure of functional response. Since these devices can be operated with human tissue samples or with in vitro tissues derived from induced pluripotent stem cells (iPS), they can play a significant role in determining the success of new pharmaceuticals, without resorting to the use of animals. By providing a platform for testing in the context of human metabolism, as opposed to animal models, the systems have the potential to eliminate the use of animals in preclinical trials. This article will review progress made and work achieved as a direct result of the 2015 Lush Science Prize in support of animal-free testing." @default.
• W2548492968 created "2016-11-11" @default.
• W2548492968 creator A5008392252 @default.
• W2548492968 creator A5022104647 @default.
• W2548492968 creator A5041397939 @default.
• W2548492968 creator A5059392894 @default.
• W2548492968 creator A5061701685 @default.
• W2548492968 date "2016-10-01" @default.
• W2548492968 modified "2023-10-16" @default.
• W2548492968 title "Body-on-a-Chip Systems for Animal-free Toxicity Testing" @default.
• W2548492968 cites W1967105697 @default.
• W2548492968 cites W1998220531 @default.
• W2548492968 cites W2008353596 @default.
• W2548492968 cites W2022941161 @default.
• W2548492968 cites W2029988210 @default.
• W2548492968 cites W2030338281 @default.
• W2548492968 cites W2030932194 @default.
• W2548492968 cites W2043972191 @default.
• W2548492968 cites W2090221057 @default.
• W2548492968 cites W2096565553 @default.
• W2548492968 cites W2099191040 @default.
• W2548492968 cites W2112791462 @default.
• W2548492968 cites W2147870969 @default.
• W2548492968 cites W2151926428 @default.
• W2548492968 cites W2172247815 @default.
• W2548492968 cites W2338259422 @default.
• W2548492968 cites W2394730474 @default.
• W2548492968 cites W241683524 @default.
• W2548492968 doi "https://doi.org/10.1177/026119291604400508" @default.
• W2548492968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27805830" @default.
• W2548492968 hasPublicationYear "2016" @default.
• W2548492968 type Work @default.
• W2548492968 sameAs 2548492968 @default.
• W2548492968 citedByCount "10" @default.
• W2548492968 countsByYear W25484929682017 @default.
• W2548492968 countsByYear W25484929682018 @default.
• W2548492968 countsByYear W25484929682019 @default.
• W2548492968 countsByYear W25484929682020 @default.
• W2548492968 crossrefType "journal-article" @default.
• W2548492968 hasAuthorship W2548492968A5008392252 @default.
• W2548492968 hasAuthorship W2548492968A5022104647 @default.
• W2548492968 hasAuthorship W2548492968A5041397939 @default.
• W2548492968 hasAuthorship W2548492968A5059392894 @default.
• W2548492968 hasAuthorship W2548492968A5061701685 @default.
• W2548492968 hasBestOaLocation W25484929681 @default.
• W2548492968 hasConcept C104317684 @default.
• W2548492968 hasConcept C105702510 @default.
• W2548492968 hasConcept C107459253 @default.
• W2548492968 hasConcept C108215921 @default.
• W2548492968 hasConcept C126322002 @default.
• W2548492968 hasConcept C127413603 @default.
• W2548492968 hasConcept C134018914 @default.
• W2548492968 hasConcept C145103041 @default.
• W2548492968 hasConcept C151730666 @default.
• W2548492968 hasConcept C169760540 @default.
• W2548492968 hasConcept C172268261 @default.
• W2548492968 hasConcept C183696295 @default.
• W2548492968 hasConcept C193293595 @default.
• W2548492968 hasConcept C2779343474 @default.
• W2548492968 hasConcept C3018263421 @default.
• W2548492968 hasConcept C3020437955 @default.
• W2548492968 hasConcept C41008148 @default.
• W2548492968 hasConcept C42407357 @default.
• W2548492968 hasConcept C55493867 @default.
• W2548492968 hasConcept C70721500 @default.
• W2548492968 hasConcept C71924100 @default.
• W2548492968 hasConcept C86803240 @default.
• W2548492968 hasConcept C98274493 @default.
• W2548492968 hasConceptScore W2548492968C104317684 @default.
• W2548492968 hasConceptScore W2548492968C105702510 @default.
• W2548492968 hasConceptScore W2548492968C107459253 @default.
• W2548492968 hasConceptScore W2548492968C108215921 @default.
• W2548492968 hasConceptScore W2548492968C126322002 @default.
• W2548492968 hasConceptScore W2548492968C127413603 @default.
• W2548492968 hasConceptScore W2548492968C134018914 @default.
• W2548492968 hasConceptScore W2548492968C145103041 @default.
• W2548492968 hasConceptScore W2548492968C151730666 @default.
• W2548492968 hasConceptScore W2548492968C169760540 @default.
• W2548492968 hasConceptScore W2548492968C172268261 @default.
• W2548492968 hasConceptScore W2548492968C183696295 @default.
• W2548492968 hasConceptScore W2548492968C193293595 @default.
• W2548492968 hasConceptScore W2548492968C2779343474 @default.
• W2548492968 hasConceptScore W2548492968C3018263421 @default.
• W2548492968 hasConceptScore W2548492968C3020437955 @default.
• W2548492968 hasConceptScore W2548492968C41008148 @default.
• W2548492968 hasConceptScore W2548492968C42407357 @default.
• W2548492968 hasConceptScore W2548492968C55493867 @default.
• W2548492968 hasConceptScore W2548492968C70721500 @default.
• W2548492968 hasConceptScore W2548492968C71924100 @default.
• W2548492968 hasConceptScore W2548492968C86803240 @default.
• W2548492968 hasConceptScore W2548492968C98274493 @default.
• W2548492968 hasIssue "5" @default.
• W2548492968 hasLocation W25484929681 @default.
• W2548492968 hasLocation W25484929682 @default.
• W2548492968 hasOpenAccess W2548492968 @default.
• W2548492968 hasPrimaryLocation W25484929681 @default.
• W2548492968 hasRelatedWork W2012911400 @default.
• W2548492968 hasRelatedWork W2035824401 @default.

• next