FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2548659650> ?p ?o ?g. }

• W2548659650 endingPage "248" @default.
• W2548659650 startingPage "242" @default.
• W2548659650 abstract "Background: Cardiac amyloidosis is an infiltrative cardiomyopathy that is challenging to diagnose. We hypothesized that the novel biomarkers hepatocyte growth factor (HGF), galectin-3 (GAL-3), interleukin-6 (IL-6), and vascular endothelial growth factor (VEGF) would be elevated in cardiac amyloidosis and may be able to discriminate from non-cardiac systemic amyloidosis or other cardiomyopathies with similar clinical or morphologic characteristics.Methods: Patients were selected from the Vanderbilt Main Heart Registry according to the following groups: (1) amyloid light-chain (AL) cardiac amyloidosis (n = 26); (2) transthyretin (ATTR) cardiac amyloidosis (n = 7); (3) left ventricular hypertrophy (LVH) (n = 45); (4) systolic heart failure (n = 42); and (5) non-cardiac systemic amyloidosis (n = 7). Biomarkers were measured in stored plasma samples. Biomarkers' discrimination performance in predicting AL cardiac amyloidosis (i.e., Concordance index) was reported. A survival analysis was used to explore the relationship between HGF levels and mortality among AL cardiac amyloidosis patients.Results: HGF levels were markedly elevated in patients with AL cardiac amyloidosis (median = 622, interquartile range (IQR): 299–1228 pg/mL) compared with the other groups, including those with non-cardiac systemic amyloidosis (median = 134, IQR: 94–163 pg/mL, p < 0.001). HGF was not a specific marker for ATTR amyloidosis. Gal-3 was elevated in all groups with amyloidosis but could not differentiate between those with and without cardiac involvement. There was no difference in IL-6 or VEGF between those with AL cardiac amyloidosis compared to other groups (p = 0.13 and 0.057, respectively).Conclusions: HGF may be a specific marker that distinguishes AL cardiac amyloidosis from other cardiomyopathies with similar clinical or morphologic characteristics. Further studies are necessary to determine whether HGF levels predict the likelihood of survival." @default.
• W2548659650 created "2016-11-11" @default.
• W2548659650 creator A5004226219 @default.
• W2548659650 creator A5010818326 @default.
• W2548659650 creator A5013155070 @default.
• W2548659650 creator A5019420069 @default.
• W2548659650 creator A5024484224 @default.
• W2548659650 creator A5030785571 @default.
• W2548659650 creator A5045593578 @default.
• W2548659650 creator A5090449848 @default.
• W2548659650 date "2016-10-01" @default.
• W2548659650 modified "2023-10-18" @default.
• W2548659650 title "Plasma hepatocyte growth factor is a novel marker of AL cardiac amyloidosis" @default.
• W2548659650 cites W1549088009 @default.
• W2548659650 cites W1784751309 @default.
• W2548659650 cites W1965108537 @default.
• W2548659650 cites W1969705003 @default.
• W2548659650 cites W1973853538 @default.
• W2548659650 cites W2007396515 @default.
• W2548659650 cites W2019823821 @default.
• W2548659650 cites W2027884835 @default.
• W2548659650 cites W2038638884 @default.
• W2548659650 cites W2053029355 @default.
• W2548659650 cites W2054721388 @default.
• W2548659650 cites W2063166582 @default.
• W2548659650 cites W2065660599 @default.
• W2548659650 cites W2070241602 @default.
• W2548659650 cites W2073420794 @default.
• W2548659650 cites W2076936565 @default.
• W2548659650 cites W2101099004 @default.
• W2548659650 cites W2106512137 @default.
• W2548659650 cites W2107403553 @default.
• W2548659650 cites W2111992555 @default.
• W2548659650 cites W2118848299 @default.
• W2548659650 cites W2128307213 @default.
• W2548659650 cites W2146578470 @default.
• W2548659650 cites W2171033052 @default.
• W2548659650 doi "https://doi.org/10.1080/13506129.2016.1242480" @default.
• W2548659650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27809600" @default.
• W2548659650 hasPublicationYear "2016" @default.
• W2548659650 type Work @default.
• W2548659650 sameAs 2548659650 @default.
• W2548659650 citedByCount "12" @default.
• W2548659650 countsByYear W25486596502017 @default.
• W2548659650 countsByYear W25486596502018 @default.
• W2548659650 countsByYear W25486596502020 @default.
• W2548659650 countsByYear W25486596502021 @default.
• W2548659650 countsByYear W25486596502022 @default.
• W2548659650 countsByYear W25486596502023 @default.
• W2548659650 crossrefType "journal-article" @default.
• W2548659650 hasAuthorship W2548659650A5004226219 @default.
• W2548659650 hasAuthorship W2548659650A5010818326 @default.
• W2548659650 hasAuthorship W2548659650A5013155070 @default.
• W2548659650 hasAuthorship W2548659650A5019420069 @default.
• W2548659650 hasAuthorship W2548659650A5024484224 @default.
• W2548659650 hasAuthorship W2548659650A5030785571 @default.
• W2548659650 hasAuthorship W2548659650A5045593578 @default.
• W2548659650 hasAuthorship W2548659650A5090449848 @default.
• W2548659650 hasConcept C119060515 @default.
• W2548659650 hasConcept C121157162 @default.
• W2548659650 hasConcept C126322002 @default.
• W2548659650 hasConcept C142724271 @default.
• W2548659650 hasConcept C159654299 @default.
• W2548659650 hasConcept C164705383 @default.
• W2548659650 hasConcept C203014093 @default.
• W2548659650 hasConcept C2777607188 @default.
• W2548659650 hasConcept C2777633098 @default.
• W2548659650 hasConcept C2778198053 @default.
• W2548659650 hasConcept C2778797674 @default.
• W2548659650 hasConcept C2779551797 @default.
• W2548659650 hasConcept C2779951007 @default.
• W2548659650 hasConcept C2779962030 @default.
• W2548659650 hasConcept C36394416 @default.
• W2548659650 hasConcept C71924100 @default.
• W2548659650 hasConcept C90924648 @default.
• W2548659650 hasConceptScore W2548659650C119060515 @default.
• W2548659650 hasConceptScore W2548659650C121157162 @default.
• W2548659650 hasConceptScore W2548659650C126322002 @default.
• W2548659650 hasConceptScore W2548659650C142724271 @default.
• W2548659650 hasConceptScore W2548659650C159654299 @default.
• W2548659650 hasConceptScore W2548659650C164705383 @default.
• W2548659650 hasConceptScore W2548659650C203014093 @default.
• W2548659650 hasConceptScore W2548659650C2777607188 @default.
• W2548659650 hasConceptScore W2548659650C2777633098 @default.
• W2548659650 hasConceptScore W2548659650C2778198053 @default.
• W2548659650 hasConceptScore W2548659650C2778797674 @default.
• W2548659650 hasConceptScore W2548659650C2779551797 @default.
• W2548659650 hasConceptScore W2548659650C2779951007 @default.
• W2548659650 hasConceptScore W2548659650C2779962030 @default.
• W2548659650 hasConceptScore W2548659650C36394416 @default.
• W2548659650 hasConceptScore W2548659650C71924100 @default.
• W2548659650 hasConceptScore W2548659650C90924648 @default.
• W2548659650 hasIssue "4" @default.
• W2548659650 hasLocation W25486596501 @default.
• W2548659650 hasOpenAccess W2548659650 @default.
• W2548659650 hasPrimaryLocation W25486596501 @default.
• W2548659650 hasRelatedWork W2021725469 @default.
• W2548659650 hasRelatedWork W2028795190 @default.

• next