Matches in SemOpenAlex for { <https://semopenalex.org/work/W2548972020> ?p ?o ?g. }
- W2548972020 abstract "Perinatal depression (PND) has an overall estimated prevalence of roughly 12 %. Untreated PND has significant negative consequences not only on the health of the mothers, but also on the physical, emotional and cognitive development of their children. No certain risk factors are known to predict PND and no completely safe drug treatments are available during pregnancy and breastfeeding. Sleep and depression are strongly related to each other because of a solid reciprocal causal relationship. Bright light therapy (BLT) is a well-tested and safe treatment, effective in both depression and circadian/sleep disorders.In a 3-year longitudinal, observational, multicentre study, about 500 women will be recruited and followed-up from early pregnancy (10-15 gestational week) until 12 months after delivery. The primary aim of the present study is to systematically explore and characterize risk factors for PND by prospective sleep assessment (using wrist actigraphy, polysomnography and various sleep questionnaires) and bloodbased analysis of potential markers during the perinatal period (Life-ON study). Secondary aims are to explore the relationship between specific genetic polymorphisms and PND (substudy Life-ON1), to investigate the effectiveness of BLT in treating PND (substudy Life-ON2) and to test whether a short term trial of BLT during pregnancy can prevent PND (substudy Life-ON3).The characterization of specific predictive and risk factors for PND may substantially contribute to improve preventive medical and social strategies for the affected women. The study results are expected to promote a better understanding of the relationship between sleep disorders and the development of PND and to confirm, in a large sample of women, the safety and efficacy of BLT both in prevention and treatment of PND.ClinicalTrials.gov NCT02664467 . Registered 13 January 2016." @default.
- W2548972020 created "2016-11-11" @default.
- W2548972020 creator A5001080390 @default.
- W2548972020 creator A5002400343 @default.
- W2548972020 creator A5009979134 @default.
- W2548972020 creator A5011558537 @default.
- W2548972020 creator A5013836575 @default.
- W2548972020 creator A5021024578 @default.
- W2548972020 creator A5025533887 @default.
- W2548972020 creator A5046041776 @default.
- W2548972020 creator A5047371267 @default.
- W2548972020 creator A5050506944 @default.
- W2548972020 creator A5052118383 @default.
- W2548972020 creator A5068124511 @default.
- W2548972020 creator A5070262261 @default.
- W2548972020 creator A5081904403 @default.
- W2548972020 creator A5085059793 @default.
- W2548972020 date "2016-11-04" @default.
- W2548972020 modified "2023-10-16" @default.
- W2548972020 title "Chronobiology, sleep-related risk factors and light therapy in perinatal depression: the “Life-ON” project" @default.
- W2548972020 cites W1427343162 @default.
- W2548972020 cites W1524720786 @default.
- W2548972020 cites W1574656550 @default.
- W2548972020 cites W1629160377 @default.
- W2548972020 cites W1682217502 @default.
- W2548972020 cites W182910583 @default.
- W2548972020 cites W185571221 @default.
- W2548972020 cites W1882949545 @default.
- W2548972020 cites W1915316839 @default.
- W2548972020 cites W1968915864 @default.
- W2548972020 cites W197066864 @default.
- W2548972020 cites W1979610528 @default.
- W2548972020 cites W1984932212 @default.
- W2548972020 cites W1996885616 @default.
- W2548972020 cites W2007567519 @default.
- W2548972020 cites W2014854833 @default.
- W2548972020 cites W2023301701 @default.
- W2548972020 cites W2028150387 @default.
- W2548972020 cites W2028702290 @default.
- W2548972020 cites W2032765500 @default.
- W2548972020 cites W2047447263 @default.
- W2548972020 cites W2052771854 @default.
- W2548972020 cites W2053623234 @default.
- W2548972020 cites W2056691704 @default.
- W2548972020 cites W2061359031 @default.
- W2548972020 cites W2061378977 @default.
- W2548972020 cites W2062161429 @default.
- W2548972020 cites W2064367814 @default.
- W2548972020 cites W2065669840 @default.
- W2548972020 cites W2066634389 @default.
- W2548972020 cites W2071191430 @default.
- W2548972020 cites W2078299157 @default.
- W2548972020 cites W2088364429 @default.
- W2548972020 cites W2088945700 @default.
- W2548972020 cites W2090211619 @default.
- W2548972020 cites W2092510383 @default.
- W2548972020 cites W2103413346 @default.
- W2548972020 cites W2108592835 @default.
- W2548972020 cites W2108609361 @default.
- W2548972020 cites W2109215279 @default.
- W2548972020 cites W2115800810 @default.
- W2548972020 cites W2117375569 @default.
- W2548972020 cites W2125086533 @default.
- W2548972020 cites W2127923250 @default.
- W2548972020 cites W2131823335 @default.
- W2548972020 cites W2132389116 @default.
- W2548972020 cites W2136452491 @default.
- W2548972020 cites W2138630297 @default.
- W2548972020 cites W2139024868 @default.
- W2548972020 cites W2140886096 @default.
- W2548972020 cites W2144392441 @default.
- W2548972020 cites W2146156330 @default.
- W2548972020 cites W2147694941 @default.
- W2548972020 cites W2149264570 @default.
- W2548972020 cites W2150056333 @default.
- W2548972020 cites W2150549140 @default.
- W2548972020 cites W2151487996 @default.
- W2548972020 cites W2214414881 @default.
- W2548972020 cites W2320427927 @default.
- W2548972020 cites W2408799309 @default.
- W2548972020 cites W2416137718 @default.
- W2548972020 cites W3041598772 @default.
- W2548972020 cites W4247665917 @default.
- W2548972020 doi "https://doi.org/10.1186/s12888-016-1086-0" @default.
- W2548972020 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5225570" @default.
- W2548972020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27814712" @default.
- W2548972020 hasPublicationYear "2016" @default.
- W2548972020 type Work @default.
- W2548972020 sameAs 2548972020 @default.
- W2548972020 citedByCount "12" @default.
- W2548972020 countsByYear W25489720202018 @default.
- W2548972020 countsByYear W25489720202019 @default.
- W2548972020 countsByYear W25489720202020 @default.
- W2548972020 countsByYear W25489720202022 @default.
- W2548972020 countsByYear W25489720202023 @default.
- W2548972020 crossrefType "journal-article" @default.
- W2548972020 hasAuthorship W2548972020A5001080390 @default.
- W2548972020 hasAuthorship W2548972020A5002400343 @default.
- W2548972020 hasAuthorship W2548972020A5009979134 @default.
- W2548972020 hasAuthorship W2548972020A5011558537 @default.