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• W2549135004 endingPage "1483" @default.
• W2549135004 startingPage "1475" @default.
• W2549135004 abstract "Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor that directs cargo proteins, such as kinases, phosphatases, and signaling receptors, to their correct location within the cell. The activity of SORLA assures proper function of cells and tissues, and receptor dysfunction is the underlying cause of common human malignancies, including Alzheimer's disease, atherosclerosis, and obesity. Here, we discuss the molecular mechanisms that govern sorting of SORLA and its cargo in multiple cell types, and why genetic defects in this receptor results in devastating diseases." @default.
• W2549135004 created "2016-11-30" @default.
• W2549135004 creator A5007732235 @default.
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• W2549135004 creator A5090601984 @default.
• W2549135004 date "2016-11-10" @default.
• W2549135004 modified "2023-10-16" @default.
• W2549135004 title "Sorting receptor SORLA: cellular mechanisms and implications for disease" @default.
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• W2549135004 doi "https://doi.org/10.1007/s00018-016-2410-z" @default.
• W2549135004 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5357279" @default.
• W2549135004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27832290" @default.
• W2549135004 hasPublicationYear "2016" @default.
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