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- W2549138812 abstract "Peripheral lung lesions are a common finding, however diagnosis is considered difficult because they cannot be visualized using conventional bronchoscopy and tissue obtained with the usual techniques may be insufficient. OBJ: To evaluate the diagnostic yield and usefulness of the combination of transbronchial cryobiopsy (TBCB) with a commercialized cryoprobe guided by RP-EBUS using a pediatric bronchoscope. METHODS: We included,03-2015 to 01-2016,patients with indication of TCB for peripheral lung lesions.After identifying the lesion by a radial ultrasonic miniprobe through a pediatric bronchoscope(BF-P180;Olympus),the TBCB were performed without guide sheath.In 2 cases fluoroscopy was also used and in one case virtual bronchoscopy simulation (LungQuest software/bronchusLungPoint systems)to calculate the trajectories to the target. Results: 10 patients were evaluated (7 men,mean age 65±11 years),9 with focal lesions.In all cases the miniprobe of RP-EBUS could be positioned within or adjacent to the lesion.The larger diameter of the focal lesions for pathologic examination was 4.4±1.9cm.7 cases were diagnosed as neoplastic disease (2likely),1 UIP and in 2 cases there were inflammatory changes.TBBperformed in 7 of the focal lesions,using both conventional forceps as cryoprobe,diagnosis of malignancy only by cryoprobe in 3(42.8%),2 of them adenocarcinoma with lepidic pattern.3 grade II bleedings occurred after TCB(30%) and no pneumothorax. CONCLUSIONS: TBCBperformed with pediatric bronchoscope and guided by RP-EBUS is a useful and feasible technique.It can increase the diagnostic yield in peripheral lung lesions compared to TBB with forceps." @default.
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- W2549138812 date "2016-09-01" @default.
- W2549138812 modified "2023-09-22" @default.
- W2549138812 title "Transbronchial cryobiopsy guided by radial probe-endobronchial ultrasound (RP-EBUS) in the diagnosis of peripheral lung lesions. Initial experience" @default.
- W2549138812 doi "https://doi.org/10.1183/13993003.congress-2016.pa4677" @default.
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