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- W2549145975 abstract "Recent imaging studies using chest computed tomography (CT) in presymptomatic infants and young children with cystic fibrosis (CF) diagnosed by newborn screening presented compelling evidence of early onset and progression of structural lung damage in CF. These data argue persuasively that non-invasive outcome measures for early detection and sensitive monitoring of lung disease applicable in the clinical setting will be instrumental for further improvement of clinical care and the development of early intervention therapies that have the potential to prevent irreversible lung damage. In this context, the use of CT imaging for early detection and long-term monitoring has the disadvantage of the risk to induce malignancies due to cumulating ionizing radiation exposure. More recently, magnetic resonance imaging (MRI) has emerged as an alternative radiation-free imaging technique for quantitative assessment of CF lung disease. In addition to structural lung damage, chest MRI enables non-invasive assessment of abnormalities in lung perfusion and ventilation characteristically associated with mucus plugging in CF lung disease. Here, we review recent developments and the prospects of MRI for improved and safer imaging with a focus on recent studies that support its utility as a sensitive non-invasive outcome measure of early lung disease in young children with CF. Pediatr Pulmonol. 2016;51:S49-S60. © 2016 Wiley Periodicals, Inc." @default.
- W2549145975 created "2016-11-30" @default.
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- W2549145975 date "2016-09-23" @default.
- W2549145975 modified "2023-10-18" @default.
- W2549145975 title "Early detection and sensitive monitoring of CF lung disease: Prospects of improved and safer imaging" @default.
- W2549145975 cites W1481320494 @default.
- W2549145975 cites W1600831640 @default.
- W2549145975 cites W1717093524 @default.
- W2549145975 cites W1770155842 @default.
- W2549145975 cites W1794263486 @default.
- W2549145975 cites W1798045062 @default.
- W2549145975 cites W1890318070 @default.
- W2549145975 cites W1909744272 @default.
- W2549145975 cites W1925481226 @default.
- W2549145975 cites W1942093492 @default.
- W2549145975 cites W1952081881 @default.
- W2549145975 cites W1963540589 @default.
- W2549145975 cites W1965152379 @default.
- W2549145975 cites W1966411814 @default.
- W2549145975 cites W1975807938 @default.
- W2549145975 cites W1978709834 @default.
- W2549145975 cites W1979706462 @default.
- W2549145975 cites W1983359381 @default.
- W2549145975 cites W1983495472 @default.
- W2549145975 cites W1986009326 @default.
- W2549145975 cites W1994869590 @default.
- W2549145975 cites W2003167821 @default.
- W2549145975 cites W2003624223 @default.
- W2549145975 cites W2005322699 @default.
- W2549145975 cites W2006001954 @default.
- W2549145975 cites W2006576990 @default.
- W2549145975 cites W2010213689 @default.
- W2549145975 cites W2011675414 @default.
- W2549145975 cites W2014597489 @default.
- W2549145975 cites W2017939832 @default.
- W2549145975 cites W2019110326 @default.
- W2549145975 cites W2020162806 @default.
- W2549145975 cites W2027616598 @default.
- W2549145975 cites W2028341547 @default.
- W2549145975 cites W2033118550 @default.
- W2549145975 cites W2033658443 @default.
- W2549145975 cites W2046716130 @default.
- W2549145975 cites W2052470792 @default.
- W2549145975 cites W2052712024 @default.
- W2549145975 cites W2064185782 @default.
- W2549145975 cites W2065660578 @default.
- W2549145975 cites W2066358248 @default.
- W2549145975 cites W2066972002 @default.
- W2549145975 cites W2077346346 @default.
- W2549145975 cites W2078678726 @default.
- W2549145975 cites W2081548537 @default.
- W2549145975 cites W2092508704 @default.
- W2549145975 cites W2093897486 @default.
- W2549145975 cites W2097982104 @default.
- W2549145975 cites W2115726200 @default.
- W2549145975 cites W2120347156 @default.
- W2549145975 cites W2124756773 @default.
- W2549145975 cites W2126375186 @default.
- W2549145975 cites W2132756075 @default.
- W2549145975 cites W2133174706 @default.
- W2549145975 cites W2136817065 @default.
- W2549145975 cites W2137263700 @default.
- W2549145975 cites W2137571255 @default.
- W2549145975 cites W2140212995 @default.
- W2549145975 cites W2140384892 @default.
- W2549145975 cites W2144292013 @default.
- W2549145975 cites W2145667093 @default.
- W2549145975 cites W2154176538 @default.
- W2549145975 cites W2154215411 @default.
- W2549145975 cites W2155094676 @default.
- W2549145975 cites W2159564206 @default.
- W2549145975 cites W2159954726 @default.
- W2549145975 cites W2163010779 @default.
- W2549145975 cites W2164555362 @default.
- W2549145975 cites W2166476126 @default.
- W2549145975 cites W2166654418 @default.
- W2549145975 cites W2166796744 @default.
- W2549145975 cites W2186656069 @default.
- W2549145975 cites W2220277228 @default.
- W2549145975 cites W2466556158 @default.
- W2549145975 cites W31831759 @default.
- W2549145975 cites W763063979 @default.
- W2549145975 cites W980856842 @default.
- W2549145975 doi "https://doi.org/10.1002/ppul.23537" @default.
- W2549145975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27662104" @default.
- W2549145975 hasPublicationYear "2016" @default.
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