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- W2549324481 abstract "Plane-wave imaging methods allow for high-speed image capture at a time interval equal to round trip acoustic propagation. Plane-wave imaging is ideally suited for cardiovascular imaging where fine-temporal resolution can reveal important information about cardiac mechanics and blood flow patterns. While plane-wave imaging has been demonstrated in humans for cardiovascular studies, its use in mouse models lags because instrumentation is not yet widely available at appropriate ultrasound frequencies. Thus, the amount of functional information that can be mined from mouse models of cardiovascular disease is limited. Here, an 18-MHz linear-array probe was used to acquire plane-wave data at a frame rate of 10 kHz from an in utero, E14.5 mouse embryo. The probe had 128 elements, 1.5 mm elevation aperture, and 8-mm elevation focus. The mother was placed supine on a heated mouse imaging platform, and then, a series of 2D + time data sequences were captured. The data were beamformed using standard delay-and-sum methods, and then, vector flow estimates were obtained at each pixel location using a least-squares, multi-angle Doppler analysis approach. Although not optimally suited for imaging mouse embryos, the 18-MHz data clearly revealed blood flow patterns in the liver, heart, and umbilical cord." @default.
- W2549324481 created "2016-11-30" @default.
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- W2549324481 date "2016-10-01" @default.
- W2549324481 modified "2023-09-23" @default.
- W2549324481 title "Plane-wave imaging of in utero mouse embryo at 18 MHz" @default.
- W2549324481 doi "https://doi.org/10.1121/1.4969399" @default.
- W2549324481 hasPublicationYear "2016" @default.
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