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- W2549362524 abstract "Onbrace is a Belgian non-interventional study evaluating the use of indacaterol (IND), a long-acting β 2 agonist indicated for COPD maintenance treatment. Known COPD patients requiring the initiation of maintenance inhaled treatment i) with IND used in monotherapy or in combination with other COPD treatment (IND group; n=1756); or ii) without IND (comparator group; n=221) were enrolled. The physician initiated the maintenance treatment per his/her current daily practice and the choice of the drugs was made at his/her own discretion. Subjective and objective measures of treatment effectiveness were collected during 6 months. Most of the enrolled patients (93%) were followed by general physicians. Per daily practice, the participating physicians included inhaled corticosteroids (ICS) as part of the first-line maintenance treatment for 50% of their patients. According to the physicians, ICS were most frequently used to improve COPD symptoms and prevent exacerbations. Prior to the study, COPD was diagnosed on the basis of clinical history (63%) and/or spirometry (45%), and was treated with short-acting bronchodilators (73%). Upon maintenance treatment initiation, an improvement in perceived treatment effectiveness, a decrease in COPD symptoms and a trend towards decrease in the number of exacerbations were observed in both groups. Few adverse events were reported ( In this study, spirometry is underused for COPD diagnosis and ICS are overused for COPD treatment (both being partly correlated) according to the GOLD document. The efficacy and the safety of IND-containing treatment are confirmed in real-life conditions." @default.
- W2549362524 created "2016-11-30" @default.
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- W2549362524 date "2016-09-01" @default.
- W2549362524 modified "2023-09-24" @default.
- W2549362524 title "Onbrace: A real-life evaluation of indacaterol maintenance treatment for COPD" @default.
- W2549362524 doi "https://doi.org/10.1183/13993003.congress-2016.pa4074" @default.
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