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- W2549385979 abstract "The first sex steroid to be crystallized was the vertebrate ovarian hormone, estrone – a less potent metabolite of 17β-estradiol, which in mammals stimulates the female urge to mate (estrus). The gadfly (Greek oistros ) lent its name to the process of estrus, as an insect that bites and torments in classical Greek mythology. With the purification and crystallization of a moult-inducing steroid (ecdysone) from insects, an interesting parallel emerged between mating and moulting in lower mammals and arthropods. Ecdysterone (potent ecdysone metabolite) has anabolic effects in mammalian muscle cells that can be blocked by selective estrogen receptor antagonists. Insects utilize ecdysteroids in similar ways that vertebrates use estrogens, including stimulation of oocyte growth and maturation. Ecdysteroids also modify precopulatory insect mating behaviour, further reinforcing the gonad-gadfly/mate-moult analogy." @default.
- W2549385979 created "2016-11-30" @default.
- W2549385979 creator A5003858441 @default.
- W2549385979 date "2017-06-01" @default.
- W2549385979 modified "2023-09-27" @default.
- W2549385979 title "On gonads and gadflies: the estrus angle" @default.
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- W2549385979 doi "https://doi.org/10.1530/joe-17-0136" @default.
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