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- W2549431134 abstract "Ulcerative colitis is a multisystemic disease associated with many extraintestinal manifestations. These various disease states can be diagnosed before, concomitant with, or after the diagnosis of ulcerative colitis. Musculoskeletal involvement is rare, and only a few cases have been reported. We report a 56-year-old man, who had migratory polyarthritis for a half year, and who presented with fever, a flare-up of polyarthritis, proximal muscle weakness, and bloody stool. U1cerative colitis, polymyositis, polyarthritis, and hepatitis were confirmed by clinical and histological evidence. The patient was refractory to high-dose corticosteroid therapy, and complicated with colon perforation. Joint pain and muscle power improved after partial colectomy, which indicated that the activity of the musculoskeletal disease paralleled that of the bowel disease. The cross-reactive peptide between the colon epithelium and the chondrocytes may provide the basis for the arthritis in ulcerative colitis. The combination of these disease entities is rare and an autoimmune link between them is likely." @default.
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- W2549431134 date "2003-08-01" @default.
- W2549431134 modified "2023-09-28" @default.
- W2549431134 title "Ulcerative Colitis Associated with Polymyositis, Polyarthritis, and Hepatitis: Response to Partial Colectomy" @default.
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