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- W2549441867 abstract "Grepafloxin has an extremely broad spectrum of activity. Its activity against Gram-positive bacteria exceeds char of currently available quinolones. Grepafloxacin-resistant mutants seem to occur less frequently than ciprofloxacin or ofloxacin-resistant mutants, and the increase in minimum inhibitory concentration (MIC) against the former mutants is less than that of the latter. This applies only to the relative differences (in dilution steps); the absolute values are similar. Grepafloxacin kills Gram-positive bacteria at concentrations little above the MIC. Its phannacodynamic profile against pneumococci is promising, favour ing use of this drug for respiratory tract infections." @default.
- W2549441867 created "2016-11-30" @default.
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- W2549441867 date "1998-01-01" @default.
- W2549441867 modified "2023-09-27" @default.
- W2549441867 title "Anti bacterial activity of grepafloxaci n" @default.
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