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• W2549526810 abstract "Endosulfan, a persistent organochlorine pesticide, is widely used in agriculture, causing negative effects on non target organisms, especially aquatic biota, including disruption of hormonal systems. However, the effect of endosulfan on fish fecundity has been hardly studied. The aims of the present study were: to determine LC of endosulfan, to investigate its propensity to induce oxidative stress, fecundity and 50 biochemical disturbances in female catfish and to study the protective role of Vitamin E (Vit. E). The results indicated that LC of endosulfan at 96h was 0.89µg/l. The absolute fecundity showed significant 50 decrease in total ripened egg number (T.R. Egg No.). The activity of acetylcholinesterase (AchE) and the level of 17s-Estradiol hormone (E ) were significantly decreased. However, endosulfan induced marked increase in 2 testosterone hormone (T), glucose and cortisol levels. Moreover, endosulfan exposure was associated with oxidative damage in liver tissue as evidenced by the increase of lipid peroxidation (LPO), catalase (CAT) and superoxide dismutase (SOD) levels and the decrease in reduced glutathione (GSH). Vit.E was effective to alleviate these toxic effects on the studied parameters. It could be concluded that Vit. E has beneficial effects and was able to antagonize endosulfan toxicity in catfish." @default.
• W2549526810 created "2016-11-30" @default.
• W2549526810 creator A5052039809 @default.
• W2549526810 date "2015-01-01" @default.
• W2549526810 modified "2023-09-24" @default.
• W2549526810 title "Vitamin E Attenuated the Oxidative Stress and Biochemical Changes Induced by Endosulfan in Female Catfish (Clarias gariepinus)" @default.
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