FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2549808439> ?p ?o ?g. }

• W2549808439 abstract "Background Hepatitis C arthropathy is one of the most important extra-hepatic manifestations of HCV. Its clinical presentation is rheumatoid like in about 30% of the cases and the differentiation between both is very important and difficult at the same time as the treatment is completely different. Anti-cyclic citrullinated peptide (Anti- CCP) antibodies can be used as serological markers in differentiation between them but many studies have variable and non-conclusive results concerning its importance. Objectives The aim of this study is to determine whether anti- CCP antibody is helpful alone in discriminating patients with HCV-associated arthropathy from patients with rheumatoid arthritis. Methods In this cross sectional comparative study we included 70 subjects, from Tanta University Hospital, Egypt and divided them into four groups: 30 Rheumatoid arthritis patients not infected with HCV,15 HCV patients with typical polyarthritis like RA without erosions or rheumatoid nodules, 15 HCV patients without arthropathy and 10 Normal subjects as a control group. We measured the level of Anti-CCP and RF in all groups. Results By the end of the study we found that anti-CCP was positive in 83.3% of RA group, 66.7% of HCV with arthropathy group, 40% of HCV without arthropathy group and in 30% of normal control group and there was a significant difference between RA group and HCV without arthropathy and control group, but there was no significant difference between RA and HCV arthropathy However during the comparison between the four groups as regard the degree of positivity of anti-CCP level there was a big difference in the degree of positivity in RA group and HCV arthropathy where 19 (63.3%) were strong positive in RA groups while only (20%)were strong positive in HCV related arthropathy. Conclusions Anti CCP can be a used as an early step in differentiating RA from HCV related arthropathy. If its level is strong positive this can highly suggest early rheumatoid arthritis but if the level is moderately positive or weak positive or even negative it is not enough alone as a marker differentiating RA from HCV related arthropathy. References Michele Bombardieri, Cristiano Alessandri, Giancarlo Labbadia ea. Role of anti-cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection-associated polyarticular involvement. Arthritis Res Ther 2004;6(2):R137–41. E Or, A C, Ayten Y, N Gr-P, Hulagu S. The positivity of rheumatoid factor and anti-cyclic citrullinated peptide antibody in nonarthritic patients with chronic hepatitis c infection. Rheumatol International 2010;30(4):485–8. M.Elnadry, Abdel-Rashed M, M.A.Abdel-Monem, S.El-Eter, Fathy W. Anti-Cyclic Citrullinated Peptide Frequency in Egyptian Patients with Chronic Hepatitis C Virus Infection with and without Articular Manifestation Journal of American Science 2013;9(11). Disclosure of Interest None declared" @default.
• W2549808439 created "2016-11-30" @default.
• W2549808439 creator A5021370295 @default.
• W2549808439 creator A5022705017 @default.
• W2549808439 creator A5041425829 @default.
• W2549808439 creator A5047889666 @default.
• W2549808439 creator A5051618237 @default.
• W2549808439 date "2016-06-01" @default.
• W2549808439 modified "2023-09-26" @default.
• W2549808439 title "SAT0498 Importance of Anti- Cyclic Citrullinated Peptide as A Marker Differentiating Hepatitis C Related Arthropathy from Rheumatoid Arthritis" @default.
• W2549808439 doi "https://doi.org/10.1136/annrheumdis-2016-eular.2430" @default.
• W2549808439 hasPublicationYear "2016" @default.
• W2549808439 type Work @default.
• W2549808439 sameAs 2549808439 @default.
• W2549808439 citedByCount "0" @default.
• W2549808439 crossrefType "journal-article" @default.
• W2549808439 hasAuthorship W2549808439A5021370295 @default.
• W2549808439 hasAuthorship W2549808439A5022705017 @default.
• W2549808439 hasAuthorship W2549808439A5041425829 @default.
• W2549808439 hasAuthorship W2549808439A5047889666 @default.
• W2549808439 hasAuthorship W2549808439A5051618237 @default.
• W2549808439 hasConcept C126322002 @default.
• W2549808439 hasConcept C142724271 @default.
• W2549808439 hasConcept C159654299 @default.
• W2549808439 hasConcept C203014093 @default.
• W2549808439 hasConcept C204787440 @default.
• W2549808439 hasConcept C2522874641 @default.
• W2549808439 hasConcept C2776164576 @default.
• W2549808439 hasConcept C2776232647 @default.
• W2549808439 hasConcept C2776408679 @default.
• W2549808439 hasConcept C2776455275 @default.
• W2549808439 hasConcept C2777077863 @default.
• W2549808439 hasConcept C2777575956 @default.
• W2549808439 hasConcept C2778917330 @default.
• W2549808439 hasConcept C2779146052 @default.
• W2549808439 hasConcept C45189115 @default.
• W2549808439 hasConcept C71924100 @default.
• W2549808439 hasConcept C90924648 @default.
• W2549808439 hasConceptScore W2549808439C126322002 @default.
• W2549808439 hasConceptScore W2549808439C142724271 @default.
• W2549808439 hasConceptScore W2549808439C159654299 @default.
• W2549808439 hasConceptScore W2549808439C203014093 @default.
• W2549808439 hasConceptScore W2549808439C204787440 @default.
• W2549808439 hasConceptScore W2549808439C2522874641 @default.
• W2549808439 hasConceptScore W2549808439C2776164576 @default.
• W2549808439 hasConceptScore W2549808439C2776232647 @default.
• W2549808439 hasConceptScore W2549808439C2776408679 @default.
• W2549808439 hasConceptScore W2549808439C2776455275 @default.
• W2549808439 hasConceptScore W2549808439C2777077863 @default.
• W2549808439 hasConceptScore W2549808439C2777575956 @default.
• W2549808439 hasConceptScore W2549808439C2778917330 @default.
• W2549808439 hasConceptScore W2549808439C2779146052 @default.
• W2549808439 hasConceptScore W2549808439C45189115 @default.
• W2549808439 hasConceptScore W2549808439C71924100 @default.
• W2549808439 hasConceptScore W2549808439C90924648 @default.
• W2549808439 hasLocation W25498084391 @default.
• W2549808439 hasOpenAccess W2549808439 @default.
• W2549808439 hasPrimaryLocation W25498084391 @default.
• W2549808439 hasRelatedWork W1993524691 @default.
• W2549808439 hasRelatedWork W2052451903 @default.
• W2549808439 hasRelatedWork W2091050375 @default.
• W2549808439 hasRelatedWork W2104109313 @default.
• W2549808439 hasRelatedWork W2105593250 @default.
• W2549808439 hasRelatedWork W2142396487 @default.
• W2549808439 hasRelatedWork W2211815650 @default.
• W2549808439 hasRelatedWork W2335367048 @default.
• W2549808439 hasRelatedWork W2355690709 @default.
• W2549808439 hasRelatedWork W2418240318 @default.
• W2549808439 hasRelatedWork W2531158752 @default.
• W2549808439 hasRelatedWork W2553991592 @default.
• W2549808439 hasRelatedWork W2568880667 @default.
• W2549808439 hasRelatedWork W2610505810 @default.
• W2549808439 hasRelatedWork W2761609900 @default.
• W2549808439 hasRelatedWork W2921330095 @default.
• W2549808439 hasRelatedWork W3000763514 @default.
• W2549808439 hasRelatedWork W3036121426 @default.
• W2549808439 hasRelatedWork W78553728 @default.
• W2549808439 hasRelatedWork W2171985207 @default.
• W2549808439 isParatext "false" @default.
• W2549808439 isRetracted "false" @default.
• W2549808439 magId "2549808439" @default.
• W2549808439 workType "article" @default.