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- W2549908624 abstract "The Calcitonin-negative neuroendocrine tumor of the thyroid (CNNET) or nonmedullary in humans is a rare tumor that arises primarily in the thyroid gland and may be mistaken for medullary thyroid carcinoma; it is characterized by the immunohistochemical (IHC) expression of neuroendocrine markers and the absence of expression for calcitonin. An Argentine dogo bitch showed a solid, compact thyroid tumor, which was IHC negative for the expression of calcitonin, carcinoembryonic antigen, thyroglobulin and S100 protein, and positive for synaptophysin and cytokeratin AE1-AE3. The Ki-67 proliferation index was low. We cite this case not only because it is the first case report of calcitonin-negative primary neuroendocrine tumor of the thyroid in dogs but also because we want to highlight the diagnostic importance of IHC in this regard." @default.
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- W2549908624 date "2016-11-18" @default.
- W2549908624 modified "2023-10-12" @default.
- W2549908624 title "Calcitonin-negative primary neuroendocrine tumor of the thyroid (nonmedullary) in a dog" @default.
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- W2549908624 doi "https://doi.org/10.4314/ovj.v6i3.10" @default.
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