FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2549938802> ?p ?o ?g. }

• W2549938802 abstract "ABSTRACT Microbial translocation, characterized by elevated levels of lipopolysaccharide (LPS) and related markers, is a common occurrence in HIV and some parasitic infections. This is usually associated with extensive inflammation and immune activation. To examine the occurrence of microbial translocation and the associated inflammatory response in asymptomatic Strongyloides stercoralis infection, we measured the plasma levels of LPS and other microbial translocation markers, acute-phase proteins, inflammatory markers, and proinflammatory cytokines in individuals with (infected [INF]) or without (uninfected [UN]) S. stercoralis infections. Finally, we also measured the levels of all of these markers in INF individuals following treatment of S. stercoralis infection. We show that INF individuals exhibit significantly higher plasma levels of microbial translocation markers (LPS, soluble CD14 [sCD14], intestinal fatty acid-binding protein [iFABP], and endotoxin core IgG antibody [EndoCAb]), acute-phase proteins (α-2 macroglobulin [α-2M], C-reactive protein [CRP], haptoglobin, and serum amyloid protein A [SAA]), inflammatory markers (matrix metalloproteinase 1 [MMP-1] and heme oxygenase 1 [HO-1]), and proinflammatory cytokines (interleukin-6 [IL-6], IL-8, monocyte chemoattractant protein 1 [MCP-1], and IL-1β) than do UN individuals. INF individuals exhibit significantly decreased levels of tissue inhibitor of metalloproteinases 4 (TIMP-4). Following treatment of S. stercoralis infection, the elevated levels of microbial translocation markers, acute-phase proteins, and inflammatory markers were all diminished. Our data thus show that S. stercoralis infection is characterized by microbial translocation and accompanying increases in levels of acute-phase proteins and markers of inflammation and provide data to suggest that microbial translocation is a feature of asymptomatic S. stercoralis infection and is associated with an inflammatory response." @default.
• W2549938802 created "2016-11-30" @default.
• W2549938802 creator A5040784287 @default.
• W2549938802 creator A5063107764 @default.
• W2549938802 creator A5067463799 @default.
• W2549938802 creator A5075129684 @default.
• W2549938802 creator A5077213465 @default.
• W2549938802 creator A5090044485 @default.
• W2549938802 date "2017-01-01" @default.
• W2549938802 modified "2023-09-24" @default.
• W2549938802 title "Microbial Translocation Associated with an Acute-Phase Response and Elevations in MMP-1, HO-1, and Proinflammatory Cytokines in Strongyloides stercoralis Infection" @default.
• W2549938802 cites W1831321011 @default.
• W2549938802 cites W191708048 @default.
• W2549938802 cites W196549982 @default.
• W2549938802 cites W1967207824 @default.
• W2549938802 cites W1967277946 @default.
• W2549938802 cites W1973651409 @default.
• W2549938802 cites W1973780740 @default.
• W2549938802 cites W1978067969 @default.
• W2549938802 cites W1981269419 @default.
• W2549938802 cites W1981694043 @default.
• W2549938802 cites W1983820446 @default.
• W2549938802 cites W1987982436 @default.
• W2549938802 cites W1988128973 @default.
• W2549938802 cites W1996468782 @default.
• W2549938802 cites W2002707751 @default.
• W2549938802 cites W2002734005 @default.
• W2549938802 cites W2003572076 @default.
• W2549938802 cites W2016603646 @default.
• W2549938802 cites W2023001867 @default.
• W2549938802 cites W2024449942 @default.
• W2549938802 cites W2024742908 @default.
• W2549938802 cites W2036630215 @default.
• W2549938802 cites W2037648387 @default.
• W2549938802 cites W2040914752 @default.
• W2549938802 cites W2050165922 @default.
• W2549938802 cites W2058846810 @default.
• W2549938802 cites W2065284764 @default.
• W2549938802 cites W2065958240 @default.
• W2549938802 cites W2071359561 @default.
• W2549938802 cites W2072162872 @default.
• W2549938802 cites W2073115364 @default.
• W2549938802 cites W2073324950 @default.
• W2549938802 cites W2082172279 @default.
• W2549938802 cites W2091961926 @default.
• W2549938802 cites W2098152094 @default.
• W2549938802 cites W2114117436 @default.
• W2549938802 cites W2122483069 @default.
• W2549938802 cites W2127025703 @default.
• W2549938802 cites W2138102959 @default.
• W2549938802 cites W2138617786 @default.
• W2549938802 cites W2146229058 @default.
• W2549938802 cites W2146488133 @default.
• W2549938802 cites W2158583133 @default.
• W2549938802 cites W2162602118 @default.
• W2549938802 cites W2171476567 @default.
• W2549938802 cites W2276727827 @default.
• W2549938802 cites W2318755291 @default.
• W2549938802 cites W2419693770 @default.
• W2549938802 cites W78059754 @default.
• W2549938802 doi "https://doi.org/10.1128/iai.00772-16" @default.
• W2549938802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5203642" @default.
• W2549938802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27821584" @default.
• W2549938802 hasPublicationYear "2017" @default.
• W2549938802 type Work @default.
• W2549938802 sameAs 2549938802 @default.
• W2549938802 citedByCount "17" @default.
• W2549938802 countsByYear W25499388022017 @default.
• W2549938802 countsByYear W25499388022019 @default.
• W2549938802 countsByYear W25499388022020 @default.
• W2549938802 countsByYear W25499388022021 @default.
• W2549938802 countsByYear W25499388022022 @default.
• W2549938802 countsByYear W25499388022023 @default.
• W2549938802 crossrefType "journal-article" @default.
• W2549938802 hasAuthorship W2549938802A5040784287 @default.
• W2549938802 hasAuthorship W2549938802A5063107764 @default.
• W2549938802 hasAuthorship W2549938802A5067463799 @default.
• W2549938802 hasAuthorship W2549938802A5075129684 @default.
• W2549938802 hasAuthorship W2549938802A5077213465 @default.
• W2549938802 hasAuthorship W2549938802A5090044485 @default.
• W2549938802 hasBestOaLocation W25499388021 @default.
• W2549938802 hasConcept C104317684 @default.
• W2549938802 hasConcept C138626823 @default.
• W2549938802 hasConcept C164027704 @default.
• W2549938802 hasConcept C165901193 @default.
• W2549938802 hasConcept C203014093 @default.
• W2549938802 hasConcept C206396517 @default.
• W2549938802 hasConcept C2776914184 @default.
• W2549938802 hasConcept C2778013117 @default.
• W2549938802 hasConcept C2778513237 @default.
• W2549938802 hasConcept C55493867 @default.
• W2549938802 hasConcept C57194454 @default.
• W2549938802 hasConcept C86803240 @default.
• W2549938802 hasConcept C8891405 @default.
• W2549938802 hasConcept C89423630 @default.
• W2549938802 hasConceptScore W2549938802C104317684 @default.
• W2549938802 hasConceptScore W2549938802C138626823 @default.
• W2549938802 hasConceptScore W2549938802C164027704 @default.
• W2549938802 hasConceptScore W2549938802C165901193 @default.
• W2549938802 hasConceptScore W2549938802C203014093 @default.

• next