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- W2550090353 abstract "Background: A clinical syndrome is a cluster of clinical findings due to underlying aetiologies and has implications for clinical practice, research and health policy. Aims: To address, “Is breathlessness that persists at rest or on minimal exertion despite the optimal treatment of underlying causes a distinct clinical syndrome and, if so, (a) what should it be called, and (b) how should it be defined? Methods: A Delphi process was conducted amongst respiratory and cardiovascular medicine/nursing, respiratory physiology, neuroimaging, intensive care, oncology, palliative care and primary care experts: 1. Consultation to define areas for the survey (n=17). 2. Three Delphi survey rounds (n= 34; n=25; n=29). Results: 1. Experts from US, Europe, Australia & Canada were consulted to frame the Delphi survey. It was agreed: i) breathlessness despite optimal treatments of underlying causes was a clinical syndrome with negative consequences for patients; ii) recognition should influence clinical practice, research, service provision and policy; iii) to put forward suggested names and definitions. 2. By survey 3: 76% respondents agreed the name, “chronic breathlessness syndrome” defined as: breathlessness even though “…evidence-based treatments of underlying pathophysiology are optimised” (66%) and “contributes to physical limitations and/or a variety of adverse psychosocial, spiritual or other consequences” (83%). The term “chronic” did not need a stated duration (80%). Conclusions: “Chronic breathlessness syndrome” is a valid and relevant clinical concept needing active diagnosis and use of evidence-based therapies to systematically reduce suffering for the millions of affected people." @default.
- W2550090353 created "2016-11-30" @default.
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- W2550090353 date "2016-09-01" @default.
- W2550090353 modified "2023-09-27" @default.
- W2550090353 title "A delphi process defining 'chronic breathlessness syndrome': A distinct clinical entity" @default.
- W2550090353 doi "https://doi.org/10.1183/13993003.congress-2016.pa3754" @default.
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