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- W2550302005 abstract "The aim of this study was to prepare Diclofenac sodium microspheres using natural polymer, i.e. Babul (Acacia nilotica) gum and show the effect of calcium chloride and barium chloride on release behavior of microspheres. The microspheres of Diclofenac sodium were successfully developed by ionic gelation technique in which calcium chloride and barium chloride were used as cross-linking agents. Ten formulations were successfully prepared i.e. F1 to F10. All the formulations were evaluated for micromeritic properties, particle size analysis, percentage yield, drug content, percent moisture loss, swelling index and in vitro dissolution studies, etc. The percentage yield of microspheres ranged from 88.23 ± 0.19% to 98.86 ± 0.21%. Batch F8 showed maximum percentage yield as compare to the other formulations. The bulk density and tapped density of babul gum loaded microspheres were in ranged from 0.68 ± 0.004 g/cm to 1.29 ± 0.001 g/cm and 33" @default.
- W2550302005 created "2016-11-30" @default.
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- W2550302005 date "2015-01-01" @default.
- W2550302005 modified "2023-09-27" @default.
- W2550302005 title "Effect of Calcium Chloride and Barium Chloride on Release Behavior of Babul (Acacia nilotica) Gum Microspheres" @default.
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