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- W2550367496 abstract "Positron emission tomography (PET) has been a widely used tool in oncology for staging lymphomas for a long time. Recently, several large clinical trials demonstrated its utility in therapy management during treatment, paving the way to personalized medicine. In doing so, the traditional way of reporting PET based on the extent of disease has been complemented by a discrete scale that takes in account tumour metabolism. However, due to several technical, physical and biological limitations in the use of PET uptake as a biomarker, stringent rules have been used in clinical trials to reduce the errors in its evaluation. Within this manuscript we will describe shortly the evolution in PET reporting, examine the main errors in uptake measurement, and analyse which strategy the clinical trials applied to reduce them." @default.
- W2550367496 created "2016-11-30" @default.
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- W2550367496 date "2016-11-15" @default.
- W2550367496 modified "2023-10-16" @default.
- W2550367496 title "The Strategies to Homogenize PET/CT Metrics: The Case of Onco-Haematological Clinical Trials" @default.
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- W2550367496 doi "https://doi.org/10.3390/biomedicines4040026" @default.
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