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- W2550384450 abstract "Tobacco Mosaic Virus: One Hundred Years of Contributions to VirologyEdited by K-B.G. Scholthof, J.G. Shaw and M. ZaitlinAPS Press, 1999.US$49.00, hbk(264 pages)ISBN 0 89054 236 8Tobacco mosaic virus (TMV) has ‘been there’for an amazing number of diverse discoveriesduring the past 100 years or so, both as a majorplayer and as an important contributor. It wasthe first infectious agent to be recognized asbeing distinct from bacteria and fungi and thusthe first to bear the designation ‘virus’. TMV’spre-eminence is also the result of the hightiters it achieves in its tobacco host, its ease ofisolation, and the single small coat proteinspecies that forms TMV’s capsid.For decades after TMV’s identification as avirus, the substance responsible for hereditywas thought to be protein. Indeed, WendellStanley, who, in haste, claimed to have crys-tallized an infectious agent consisting solely ofprotein, initially missed the nucleic acid con-tent of TMV. The later finding that the onlyother virion component – the RNA – wasinfectious by itself, bolstered evidence that thenucleic acid was the genetic material, as didthe finding that virions assembled from proteinand RNA from different sources producedinfections characteristic of those caused by theRNA source" @default.
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- W2550384450 date "2000-01-01" @default.
- W2550384450 modified "2023-09-24" @default.
- W2550384450 title "Historical of TMV Tobacco Mosaic Virus: One Hundred Years of Contributions to Virology" @default.
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