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- W2550409090 abstract "Thispaperattemptstoexplainwhy,againstseeminglyoverwhelmingodds,certain organismscantoleratefreezingtolowtemperatures,whysomeattemptstoimitate thisinnontolerantorganismshavebeenpartiallysuccessful,andwhynarrowly constrainedratesofdrying,coolingandheatingarecriticaltothatsuccess.Below theicepoint,temperatureloweringreducesthevapourpressureofwater,andthe semipermeabilityofmembranesimposesalargemechanicalor'osmotic'stresson cellswhichundergoadeformation,orstrain,borneprincipallybythecytoskele ton.Nonetheless,evenlethalstressescanhavetheireffectsdeferredforminutesor evenhours,providinga'window'forcryopreservation.Weproposethatbecause theconnectionbetweenstressandstrainisnotelasticbutviscoelastic,thestrainis spreadover time and its intensitydiluted. Beyondlimits oftimeandintensity, relaxationinthecytoskeletonwillbecomeirreversible.WeofferanAvramimodel inwhichanArrheniusexpressionmodelsthetemperatureeffectandelasticmoduli supplyanactivationenergy, toprovidea rationalbasisfor thedevelopmentof cryopreservationtechniques." @default.
- W2550409090 created "2016-11-30" @default.
- W2550409090 creator A5015608827 @default.
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- W2550409090 date "1997-01-01" @default.
- W2550409090 modified "2023-09-23" @default.
- W2550409090 title "79.FreezingStress,OsmoticStrain,andtheir ViscoelasticCoupling" @default.
- W2550409090 cites W2078524135 @default.
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- W2550409090 hasPublicationYear "1997" @default.
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