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- W2550524794 abstract "A new series of chiral 5-substituted bis-oxazolidinones containing an acylsulfonamide moiety has been synthesized starting from chlorosulfonyl isocyanate, (l)-ethyl lactate, and oxazolidin-2-ones. All the reactions were conducted at ambient temperature, and the N-acylsulfonamide bis-oxazolidin-2-ones were obtained with high yields within 2 h. Some of the newly synthesized compounds were evaluated in vitro against the virulent strain RH of Toxoplasma gondii and the human lymphocytes, and showed promising results." @default.
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- W2550524794 date "2013-09-09" @default.
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- W2550524794 title "Synthesis and Biological Activity of New Chiral<i>N</i>-Acylsulfonamide Bis-oxazolidin-2-ones" @default.
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- W2550524794 doi "https://doi.org/10.1002/jhet.1987" @default.
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