Matches in SemOpenAlex for { <https://semopenalex.org/work/W2550841788> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2550841788 endingPage "13" @default.
- W2550841788 startingPage "309" @default.
- W2550841788 abstract "Factor V Leiden (FVL), prothrombin gene (PT G20210A) and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms are the main biomarkers used in the evaluation of tendency to venous thromboembolism. Our study aimed to investigate the distribution frequencies of these polymorphisms in healthy Turks living in the urban Yozgat region. This study included 90 blood donor candidates. All the donors were apparently healthy, and there was no family relationship between them. Mutations including FVL, PT G20210A, and MTHFR (C677T, A1298C) were investigated in all participants. Screening of polymorphisms was carried out using the SNaPshot® multiplex system.There were 42 male and 48 female individuals with age range 17-78 years and mean age 47.5 ± 13.6 years. The heterozygous FVL mutation was noted in 17 (10 male and seven female) donors (19%). FVL mutation was more frequently encountered in males than in females (23.8% vs. 12.5%). The heterozygous PT G20210A mutation was observed in five (5.5%) of the 90 (three male, two female) donors. The prevalence of homozygous polymorphisms of MTHFR C677T was 8.8% and of MTHFR A1298C 13.3%. On the other hand, four of the 90 participants (4.4%) carried none of these polymorphisms.This study showed that the prevalence of FVL, PT G20210A, MTHFR C677T and MTHFR A1298C polymorphisms is quite high, and the coexistence of FVL with other genotypes is not rare in a healthy Turkish population living in the Yozgat region. Of course, further detailed studies should be performed to support these findings. Hippokratia 2015; 19 (4): 309-313." @default.
- W2550841788 created "2016-11-30" @default.
- W2550841788 creator A5021307286 @default.
- W2550841788 creator A5027017459 @default.
- W2550841788 creator A5036207597 @default.
- W2550841788 date "2016-10-01" @default.
- W2550841788 modified "2023-09-27" @default.
- W2550841788 title "The prevalence of Factor V Leiden, prothrombin G20210A, MTHFR C677T and MTHFR A1298C mutations in healthy Turkish population." @default.
- W2550841788 cites W1531281563 @default.
- W2550841788 cites W1924149582 @default.
- W2550841788 cites W1975205346 @default.
- W2550841788 cites W1979445535 @default.
- W2550841788 cites W1984926454 @default.
- W2550841788 cites W1986559703 @default.
- W2550841788 cites W1989143755 @default.
- W2550841788 cites W1995474189 @default.
- W2550841788 cites W2015371302 @default.
- W2550841788 cites W2015463393 @default.
- W2550841788 cites W2030930589 @default.
- W2550841788 cites W2064684709 @default.
- W2550841788 cites W2066002619 @default.
- W2550841788 cites W2083581286 @default.
- W2550841788 cites W2121507070 @default.
- W2550841788 cites W2140406731 @default.
- W2550841788 cites W2140707981 @default.
- W2550841788 cites W2151933426 @default.
- W2550841788 cites W2156775126 @default.
- W2550841788 cites W2166110276 @default.
- W2550841788 cites W2170440742 @default.
- W2550841788 cites W2179963321 @default.
- W2550841788 cites W2332729973 @default.
- W2550841788 cites W2467027916 @default.
- W2550841788 cites W2476581531 @default.
- W2550841788 cites W2616334313 @default.
- W2550841788 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5033140" @default.
- W2550841788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27688694" @default.
- W2550841788 hasPublicationYear "2016" @default.
- W2550841788 type Work @default.
- W2550841788 sameAs 2550841788 @default.
- W2550841788 citedByCount "6" @default.
- W2550841788 countsByYear W25508417882017 @default.
- W2550841788 countsByYear W25508417882018 @default.
- W2550841788 countsByYear W25508417882020 @default.
- W2550841788 countsByYear W25508417882022 @default.
- W2550841788 countsByYear W25508417882023 @default.
- W2550841788 crossrefType "journal-article" @default.
- W2550841788 hasAuthorship W2550841788A5021307286 @default.
- W2550841788 hasAuthorship W2550841788A5027017459 @default.
- W2550841788 hasAuthorship W2550841788A5036207597 @default.
- W2550841788 hasConcept C104317684 @default.
- W2550841788 hasConcept C126322002 @default.
- W2550841788 hasConcept C135763542 @default.
- W2550841788 hasConcept C2776046644 @default.
- W2550841788 hasConcept C2777175894 @default.
- W2550841788 hasConcept C2777872019 @default.
- W2550841788 hasConcept C2778817970 @default.
- W2550841788 hasConcept C2780011451 @default.
- W2550841788 hasConcept C2780868729 @default.
- W2550841788 hasConcept C29456083 @default.
- W2550841788 hasConcept C43563269 @default.
- W2550841788 hasConcept C54355233 @default.
- W2550841788 hasConcept C71924100 @default.
- W2550841788 hasConcept C86803240 @default.
- W2550841788 hasConcept C90924648 @default.
- W2550841788 hasConceptScore W2550841788C104317684 @default.
- W2550841788 hasConceptScore W2550841788C126322002 @default.
- W2550841788 hasConceptScore W2550841788C135763542 @default.
- W2550841788 hasConceptScore W2550841788C2776046644 @default.
- W2550841788 hasConceptScore W2550841788C2777175894 @default.
- W2550841788 hasConceptScore W2550841788C2777872019 @default.
- W2550841788 hasConceptScore W2550841788C2778817970 @default.
- W2550841788 hasConceptScore W2550841788C2780011451 @default.
- W2550841788 hasConceptScore W2550841788C2780868729 @default.
- W2550841788 hasConceptScore W2550841788C29456083 @default.
- W2550841788 hasConceptScore W2550841788C43563269 @default.
- W2550841788 hasConceptScore W2550841788C54355233 @default.
- W2550841788 hasConceptScore W2550841788C71924100 @default.
- W2550841788 hasConceptScore W2550841788C86803240 @default.
- W2550841788 hasConceptScore W2550841788C90924648 @default.
- W2550841788 hasIssue "4" @default.
- W2550841788 hasLocation W25508417881 @default.
- W2550841788 hasOpenAccess W2550841788 @default.
- W2550841788 hasPrimaryLocation W25508417881 @default.
- W2550841788 hasRelatedWork W2016720146 @default.
- W2550841788 hasRelatedWork W2022848815 @default.
- W2550841788 hasRelatedWork W2120940095 @default.
- W2550841788 hasRelatedWork W2130321663 @default.
- W2550841788 hasRelatedWork W2329080395 @default.
- W2550841788 hasRelatedWork W2410021146 @default.
- W2550841788 hasRelatedWork W2550841788 @default.
- W2550841788 hasRelatedWork W2576686934 @default.
- W2550841788 hasRelatedWork W3012862533 @default.
- W2550841788 hasRelatedWork W1514603520 @default.
- W2550841788 hasVolume "19" @default.
- W2550841788 isParatext "false" @default.
- W2550841788 isRetracted "false" @default.
- W2550841788 magId "2550841788" @default.
- W2550841788 workType "article" @default.