FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2551073887> ?p ?o ?g. }

• W2551073887 endingPage "139" @default.
• W2551073887 startingPage "132" @default.
• W2551073887 abstract "Background and objectives To date, it is unclear whether antigen matching is effective in reducing antibody development and whether transfusing blood from non‐Caucasian donors reduces alloimmunization in sickle cell disease patients ( SCP ). This study was designed to evaluate the effectiveness of an antigen‐matching strategy supplied by a mixed donor population, in reducing alloimmunization in SCP s. Methods Eighty SCP s transfused with C‐, E‐ and K‐matched units and 2000 donors were genotyped for the most relevant RBC antigens, and resulting genotypic frequencies were compared. Also, alloantibodies specificity and clinical complications were evaluated in SCP s. Results A high alloimmunization rate was observed despite the prophylaxis protocol (62·1%). The main cause underlying lack of effectiveness was transfusion of non‐matched units in external hospitals. Even though our donor population was ethnically mixed, it still exhibited antigenic differences in relation to SCP s (C and Fy a ). Frequency of clinical complications was similar between alloimmunized and non‐alloimmunized patients. Conclusions Prospective antigen matching is an unattractive alloimmunization prophylaxis for SCP s if not associated with strategies to minimize the hazards related to transfusions at non‐index hospitals. Even in a highly mixed donor population, antigenic discrepancies in SCP s are high, increasing the risk of antibody development." @default.
• W2551073887 created "2016-11-30" @default.
• W2551073887 creator A5016234525 @default.
• W2551073887 creator A5018500550 @default.
• W2551073887 creator A5021037940 @default.
• W2551073887 creator A5032544285 @default.
• W2551073887 creator A5033668012 @default.
• W2551073887 creator A5035676777 @default.
• W2551073887 creator A5038611071 @default.
• W2551073887 creator A5047861224 @default.
• W2551073887 creator A5053650706 @default.
• W2551073887 creator A5069859243 @default.
• W2551073887 creator A5071061513 @default.
• W2551073887 creator A5079367966 @default.
• W2551073887 creator A5081451790 @default.
• W2551073887 creator A5091722441 @default.
• W2551073887 date "2016-11-15" @default.
• W2551073887 modified "2023-10-16" @default.
• W2551073887 title "Effectiveness of a red cell antigen-matching transfusion protocol in sickle cell disease patients" @default.
• W2551073887 cites W1551946963 @default.
• W2551073887 cites W1602176128 @default.
• W2551073887 cites W1720270056 @default.
• W2551073887 cites W1764651538 @default.
• W2551073887 cites W1857762722 @default.
• W2551073887 cites W1927812827 @default.
• W2551073887 cites W1958587427 @default.
• W2551073887 cites W1976293536 @default.
• W2551073887 cites W2033087161 @default.
• W2551073887 cites W2035718279 @default.
• W2551073887 cites W2048073127 @default.
• W2551073887 cites W2048176236 @default.
• W2551073887 cites W2066481736 @default.
• W2551073887 cites W2080527847 @default.
• W2551073887 cites W2100159652 @default.
• W2551073887 cites W2117679170 @default.
• W2551073887 cites W2121464179 @default.
• W2551073887 cites W2125636692 @default.
• W2551073887 cites W2136460998 @default.
• W2551073887 cites W2154470508 @default.
• W2551073887 cites W2156174439 @default.
• W2551073887 cites W2163125609 @default.
• W2551073887 cites W2196780263 @default.
• W2551073887 doi "https://doi.org/10.1111/voxs.12281" @default.
• W2551073887 hasPublicationYear "2016" @default.
• W2551073887 type Work @default.
• W2551073887 sameAs 2551073887 @default.
• W2551073887 citedByCount "13" @default.
• W2551073887 countsByYear W25510738872017 @default.
• W2551073887 countsByYear W25510738872018 @default.
• W2551073887 countsByYear W25510738872019 @default.
• W2551073887 countsByYear W25510738872020 @default.
• W2551073887 countsByYear W25510738872021 @default.
• W2551073887 countsByYear W25510738872022 @default.
• W2551073887 countsByYear W25510738872023 @default.
• W2551073887 crossrefType "journal-article" @default.
• W2551073887 hasAuthorship W2551073887A5016234525 @default.
• W2551073887 hasAuthorship W2551073887A5018500550 @default.
• W2551073887 hasAuthorship W2551073887A5021037940 @default.
• W2551073887 hasAuthorship W2551073887A5032544285 @default.
• W2551073887 hasAuthorship W2551073887A5033668012 @default.
• W2551073887 hasAuthorship W2551073887A5035676777 @default.
• W2551073887 hasAuthorship W2551073887A5038611071 @default.
• W2551073887 hasAuthorship W2551073887A5047861224 @default.
• W2551073887 hasAuthorship W2551073887A5053650706 @default.
• W2551073887 hasAuthorship W2551073887A5069859243 @default.
• W2551073887 hasAuthorship W2551073887A5071061513 @default.
• W2551073887 hasAuthorship W2551073887A5079367966 @default.
• W2551073887 hasAuthorship W2551073887A5081451790 @default.
• W2551073887 hasAuthorship W2551073887A5091722441 @default.
• W2551073887 hasConcept C126322002 @default.
• W2551073887 hasConcept C147483822 @default.
• W2551073887 hasConcept C159654299 @default.
• W2551073887 hasConcept C203014093 @default.
• W2551073887 hasConcept C2779134260 @default.
• W2551073887 hasConcept C2908647359 @default.
• W2551073887 hasConcept C71924100 @default.
• W2551073887 hasConcept C99454951 @default.
• W2551073887 hasConceptScore W2551073887C126322002 @default.
• W2551073887 hasConceptScore W2551073887C147483822 @default.
• W2551073887 hasConceptScore W2551073887C159654299 @default.
• W2551073887 hasConceptScore W2551073887C203014093 @default.
• W2551073887 hasConceptScore W2551073887C2779134260 @default.
• W2551073887 hasConceptScore W2551073887C2908647359 @default.
• W2551073887 hasConceptScore W2551073887C71924100 @default.
• W2551073887 hasConceptScore W2551073887C99454951 @default.
• W2551073887 hasFunder F4320320997 @default.
• W2551073887 hasIssue "3" @default.
• W2551073887 hasLocation W25510738871 @default.
• W2551073887 hasOpenAccess W2551073887 @default.
• W2551073887 hasPrimaryLocation W25510738871 @default.
• W2551073887 hasRelatedWork W1974142213 @default.
• W2551073887 hasRelatedWork W2033739428 @default.
• W2551073887 hasRelatedWork W2040191638 @default.
• W2551073887 hasRelatedWork W2048473435 @default.
• W2551073887 hasRelatedWork W2053424985 @default.
• W2551073887 hasRelatedWork W2092538248 @default.
• W2551073887 hasRelatedWork W2220102944 @default.
• W2551073887 hasRelatedWork W2229562627 @default.

• next