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- W2551100637 abstract "Background: Inhaled treatment (bronchodilators and corticosteroids [ICs]) in patients with bronchiectasis (BE) was extrapolated from asthma or COPD but without strong scientific evidence Objective: To assess characteristics of BE patients with an exacerbation in relation to the chronic use of ICs Methods: Multicentre prospective study of consecutive exacerbations from 4 Spanish hospitals. Population was classified according to previous ICs use Results: We collect 186 BE exacerbations (29% with pneumonia); in 144 cases (77%) previous ICs were recorded. Patients9 demographics were similar in both groups. Vaccination, exacerbations, chronic bronchial infection, asthma, and severity of BE were increased in ICs group. Clinical presentatiom, microbiology, outcomes and complications did not differ according to ICs. Overall, 26% patients with ICs and 36% without ICs had pneumonia. In pneumonia cases, ICs did not show any association with microbiology, outcomes or complications, excepting less severe sepsis (3% vs 20%;p=0.031) Conclusions: ICs were more frequent in patients with concomitant asthma and increased BE severity (BSI, exacerbations, etc.). The ICs group had a non-significant trend to lower rate of pneumonia and to less severe sepsis. ICs did not show any association with clinical presentation, microbiology and outcomes. Further investigation is needed to assess the role of ICs in the risk of CAP and related outcomes in BE." @default.
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- W2551100637 date "2016-09-01" @default.
- W2551100637 modified "2023-10-17" @default.
- W2551100637 title "Chronic inhaled corticosteroids in patients with bronchiectasis who suffer an exacerbation" @default.
- W2551100637 doi "https://doi.org/10.1183/13993003.congress-2016.pa1548" @default.
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