FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2551102177> ?p ?o ?g. }

• W2551102177 abstract "Dexmedetomidine, a selective alpha-2 agonist, has sedative, analgesic, and anxiolytic effects without respiratory depression. Dexmedetomidine can cause a biphasic cardiovascular response, and induce transient hypertension. Hypotension is a common complication of spinal anesthesia. Decreasing anxiety of patients before procedure is important for high quality of procedure. This study aimed to compare the incidence of hypotension and patients’ anxiety and comfort levels when dexmedetomidine was intravenously administered before and after spinal anesthesia. Seventy-four patients with American Society of Anesthesiologists physical status classification I or II were randomly allocated into two groups. Spinal anesthesia was performed using 12 mg of 0.5% heavy bupivacaine. In Group A, 1 μg/kg of dexmedetomidine was intravenously administered for 10 min, followed by the maintenance infusion of dexmedetomidine 0.2 μg/kg/hr after 5 min of intrathecal bupivacaine injection. Patients in Group B received same dose of dexmedetomidine by intravenous administration before 5 min of intrathecal bupivacaine injection. Perioperative vital signs, anxiety (using the Spielberger’s State-Trait Anxiety Inventory) and comfort (using the numerical rating scale) were evaluated. The incidence of hypotension was significantly lower in Group A (16.1%) than in Group B (48.4%) during infusion of dexmedetomidine (p = 0.01). The need for treatment of hypotension is higher in Group B than Group A (p = 0.02). The incidence of bradycardia and desaturation did not significantly differ between the two groups. There were no statistically significant differences regarding the patients’ anxiety and comfort. Hypotension is more frequently occurred, and the treatment of hypotension is more needed in Group B. The intravenously administration of dexmedetomidine before spinal anesthesia has no advantages in hemodynamic status and patients’ comfort compared to that after spinal anesthesia during lower limb surgery. ClinicalTrials.gov number, NCT02155010 . Retrospectively registered on May 22, 2014." @default.
• W2551102177 created "2016-11-30" @default.
• W2551102177 creator A5033004945 @default.
• W2551102177 creator A5033862186 @default.
• W2551102177 creator A5042198881 @default.
• W2551102177 creator A5051594382 @default.
• W2551102177 creator A5057608258 @default.
• W2551102177 creator A5060544438 @default.
• W2551102177 creator A5085903475 @default.
• W2551102177 creator A5087825335 @default.
• W2551102177 date "2016-11-21" @default.
• W2551102177 modified "2023-10-07" @default.
• W2551102177 title "The timing of administration of intravenous dexmedetomidine during lower limb surgery: a randomized controlled trial" @default.
• W2551102177 cites W1480393032 @default.
• W2551102177 cites W1609915549 @default.
• W2551102177 cites W1971101248 @default.
• W2551102177 cites W1977440968 @default.
• W2551102177 cites W1982653554 @default.
• W2551102177 cites W1995696853 @default.
• W2551102177 cites W2000018178 @default.
• W2551102177 cites W2008846813 @default.
• W2551102177 cites W2014856731 @default.
• W2551102177 cites W2045421520 @default.
• W2551102177 cites W2046624819 @default.
• W2551102177 cites W2067978100 @default.
• W2551102177 cites W2083120825 @default.
• W2551102177 cites W2100223992 @default.
• W2551102177 cites W2106145112 @default.
• W2551102177 cites W2108980610 @default.
• W2551102177 cites W2118303527 @default.
• W2551102177 cites W2134777799 @default.
• W2551102177 cites W2159176145 @default.
• W2551102177 cites W2162845029 @default.
• W2551102177 cites W2168312394 @default.
• W2551102177 cites W2221877984 @default.
• W2551102177 cites W4236541079 @default.
• W2551102177 doi "https://doi.org/10.1186/s12871-016-0282-2" @default.
• W2551102177 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5117579" @default.
• W2551102177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27871236" @default.
• W2551102177 hasPublicationYear "2016" @default.
• W2551102177 type Work @default.
• W2551102177 sameAs 2551102177 @default.
• W2551102177 citedByCount "4" @default.
• W2551102177 countsByYear W25511021772018 @default.
• W2551102177 countsByYear W25511021772019 @default.
• W2551102177 countsByYear W25511021772023 @default.
• W2551102177 crossrefType "journal-article" @default.
• W2551102177 hasAuthorship W2551102177A5033004945 @default.
• W2551102177 hasAuthorship W2551102177A5033862186 @default.
• W2551102177 hasAuthorship W2551102177A5042198881 @default.
• W2551102177 hasAuthorship W2551102177A5051594382 @default.
• W2551102177 hasAuthorship W2551102177A5057608258 @default.
• W2551102177 hasAuthorship W2551102177A5060544438 @default.
• W2551102177 hasAuthorship W2551102177A5085903475 @default.
• W2551102177 hasAuthorship W2551102177A5087825335 @default.
• W2551102177 hasBestOaLocation W25511021771 @default.
• W2551102177 hasConcept C126322002 @default.
• W2551102177 hasConcept C141071460 @default.
• W2551102177 hasConcept C168563851 @default.
• W2551102177 hasConcept C2776814716 @default.
• W2551102177 hasConcept C2777495988 @default.
• W2551102177 hasConcept C2777602617 @default.
• W2551102177 hasConcept C2777953023 @default.
• W2551102177 hasConcept C2779526319 @default.
• W2551102177 hasConcept C2781302539 @default.
• W2551102177 hasConcept C2781328992 @default.
• W2551102177 hasConcept C31174226 @default.
• W2551102177 hasConcept C42219234 @default.
• W2551102177 hasConcept C71924100 @default.
• W2551102177 hasConcept C84393581 @default.
• W2551102177 hasConceptScore W2551102177C126322002 @default.
• W2551102177 hasConceptScore W2551102177C141071460 @default.
• W2551102177 hasConceptScore W2551102177C168563851 @default.
• W2551102177 hasConceptScore W2551102177C2776814716 @default.
• W2551102177 hasConceptScore W2551102177C2777495988 @default.
• W2551102177 hasConceptScore W2551102177C2777602617 @default.
• W2551102177 hasConceptScore W2551102177C2777953023 @default.
• W2551102177 hasConceptScore W2551102177C2779526319 @default.
• W2551102177 hasConceptScore W2551102177C2781302539 @default.
• W2551102177 hasConceptScore W2551102177C2781328992 @default.
• W2551102177 hasConceptScore W2551102177C31174226 @default.
• W2551102177 hasConceptScore W2551102177C42219234 @default.
• W2551102177 hasConceptScore W2551102177C71924100 @default.
• W2551102177 hasConceptScore W2551102177C84393581 @default.
• W2551102177 hasIssue "1" @default.
• W2551102177 hasLocation W25511021771 @default.
• W2551102177 hasLocation W25511021772 @default.
• W2551102177 hasLocation W25511021773 @default.
• W2551102177 hasLocation W25511021774 @default.
• W2551102177 hasOpenAccess W2551102177 @default.
• W2551102177 hasPrimaryLocation W25511021771 @default.
• W2551102177 hasRelatedWork W2110127181 @default.
• W2551102177 hasRelatedWork W2126545071 @default.
• W2551102177 hasRelatedWork W2341116565 @default.
• W2551102177 hasRelatedWork W2367312788 @default.
• W2551102177 hasRelatedWork W2520630385 @default.
• W2551102177 hasRelatedWork W2580873553 @default.
• W2551102177 hasRelatedWork W2898264542 @default.
• W2551102177 hasRelatedWork W3153296609 @default.
• W2551102177 hasRelatedWork W4210887191 @default.

• next