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- W255122022 abstract "Abstract : As has been reported earlier, PMB conjugated to either Bovine Serum Albumin (BSA) or Keyhole Limpet Hemocyanin (KLH) were very immunogenic in both rabbits and Balb/c mice. The latter was not as immunogenic as the PMB-BSA conjugate largely because of it insoluble state. Both preparations have lost significant antibacterial properties suggesting that a significant number of the diaminobutyric acids were substituted by the conjugation process. The conjugated PMB preparations were still toxic to mice when given intravenously in 2 ug quantity. Multiple intraperitoneal or subcutaneous injections of 100 ug of PMB-BSA in the presence of Freund's adjuvants stimulated the production of high levels of PMB-specific antibodies in Balb-c mice." @default.
- W255122022 created "2016-06-24" @default.
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- W255122022 date "1991-01-23" @default.
- W255122022 modified "2023-09-27" @default.
- W255122022 title "Polymyxin B(PMB)-Specific Monoclonal Antibodies" @default.
- W255122022 doi "https://doi.org/10.21236/ada231817" @default.
- W255122022 hasPublicationYear "1991" @default.
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