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• W2551286661 abstract "To evaluate the effect of vitamin D supplementation on patients with PCOS.We performed a literature search in database and identified all of the RCTs published before December 2015 that compared the effect of vitamin D supplementation with placebo or metformin in PCOS patients.Nine out of 463 identified studies were included, involving 502 women presenting with PCOS. Vitamin D supplementation had significant effect on the improvement of follicular development with a higher number of dominant follicles (OR, 2.34; 95% CI, 1.39 to 3.92). Differences in regular menstrual cycles were also observed when metformin plus vitamin D was compared with metformin alone (OR, 1.85; 95% CI, 1.01 to 3.39).Evidence from available RCTs suggests vitamin D supplementation may be beneficial for follicular development and menstrual cycle regulation in patients with PCOS. Additional high-quality RCTs are required to confirm the effectiveness of vitamin D on PCOS." @default.
• W2551286661 created "2016-11-30" @default.
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• W2551286661 date "2017-02-01" @default.
• W2551286661 modified "2023-10-10" @default.
• W2551286661 title "Effect of vitamin D supplementation on polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials" @default.
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• W2551286661 doi "https://doi.org/10.1016/j.ctcp.2016.11.008" @default.
• W2551286661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28107851" @default.
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