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- W2551364513 abstract "A challenging problem of modern surface-enhanced Raman spectroscopy (SERS) analysis is related to the design of new composite materials with bioprotective properties providing either a reproducible signal of small quantities or intactness of protein molecules. A new way of modification of silver-based SERS-active substrates with polymer materials is proposed here to achieve large enhancement factors of SERS signals for hemoproteins. It is found that the factors grow in the order: chitosan < bare silver < alginic acid sodium salt ≤ polyacrylic acid. This demonstrates an important role of the polymer origin and its charge state in the retention of protein on the sensor surface and protecting the proteins from silver ions of the nanostructured layer in the sake of future medical diagnostics." @default.
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- W2551364513 date "2016-12-20" @default.
- W2551364513 modified "2023-10-14" @default.
- W2551364513 title "Bioprotective polymer layers for surface-enhanced Raman spectroscopy of proteins" @default.
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- W2551364513 doi "https://doi.org/10.1080/10667857.2016.1265758" @default.
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