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- W255177486 abstract "Publisher Summary This chapter describes the release and turnover of the adrenergic transmitter. The splenic nerves are excited at physiological frequencies of 10/s, or less and very little of the liberated transmitter overflows into the blood stream. The amount escaping can be increased either by exciting the nerves at higher frequencies up to 30/s, or by giving a blocking agent like phenoxybenzamine. The collection of blood during and just after stimulation involves a total loss to the system of any transmitter that overflows into this blood. When the transmitter loss is small, there is no decline in the overflow/ stimulus, and at frequencies of stimulation of 10/s the overflow/stimulus may even rise during successive trains of stimuli. When transmitter loss is high, there is an approximately exponential decline of overflow and the steepness of the decline being a function of the overflow/stimulus. The response of the spleen, measured in terms of the area of pressor response follows closely the changes in overflow." @default.
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- W255177486 date "1966-01-01" @default.
- W255177486 modified "2023-09-25" @default.
- W255177486 title "RELEASE AND TURNOVER OF THE ADRENERGIC TRANSMITTER" @default.
- W255177486 cites W2009156812 @default.
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- W255177486 doi "https://doi.org/10.1016/b978-0-08-011698-3.50020-6" @default.
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