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- W2551796369 abstract "105 Background --This study was conducted to evaluate the value of serum troponin T and creatine kinase (CK)-MB concentrations for ruling out perioperative myocardial infarction (PMI) early after cardiac surgery. Design: Prospective study. Setting: Recovery room of a tertiary hospital. Patients: Twenty three patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass were included. Methods --Serum concentrations of troponin T and CK-MB concentrations were measured preoperatively (baseline), on arrival at the recovery room (RR), and at 0, 8, 16, and 24 h after arrival at the RR. The strength of markers studied for ruling out PMI was studied using receiver operating characteristics (ROC) curves. Based on these curves, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for each marker at every time point were calculated. Results --PMI developed in 2 patients. On arrival at the RR, all markers were significantly increased from baseline concentrations in both patient groups. In patients with PMI, serum concentrations of troponin T and CK-MB were significantly higher than in control patients from 8, 16, and 24 hours after arrival at the RR. CK-MB concentration was the earliest marker, and its NPV reached 98.6% 8 hours after arrival at the RR. On arrival at the RR, the NPV for CKMB concentration already reached 96.7%. Troponin T was not an early marker for ruling out PMI, with an NPV reaching 98.6% 8 hours after arrival at the RR. During the first 8 hours after arrival at the RR, sensitivity, specificity, PPV, and NPV of CK-MB exceeded that of troponin T. Conclusion --For ruling out PMI at the RR after CABG, CK-MB is a better marker than troponin T during the first 8 hour after arrival at the RR. Using these markers, postoperative treatment of cardiac surgical patients might be further improved. Phil Heart Center J 2007; 13(2):105-108." @default.
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- W2551796369 date "2007-01-01" @default.
- W2551796369 modified "2023-09-27" @default.
- W2551796369 title "Evaluation of Cardiac Markers for Ruling Out Myocardial Infarction After Coronary Artery Bypass Grafting in Patients" @default.
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