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- W2551946382 abstract "An indirect spectrophotometric method is developed for the determination of benzocaine as pure and in pharmaceutical preparations. The method is based on the oxidation of benzocaine with iron (ΙΙΙ) in acidic medium, and the liberated iron (ΙΙ) reacts with 1,10 -phenanthroline to produce ferroin complex which has a maximum absorption at 510 nm against reagent blank. Beer’s law is valid over the concentration range of 5-80 µg benzocaine/25 ml and the molar absorptivity is 5.7 ×104 l.mol-1.cm-1, indicating high sensitivity. The common excipients and additives do not interfere in benzocaine determination. The proposed method is successfully applied to the assay of benzocaine in two synthetic preparations." @default.
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- W2551946382 date "2009-01-28" @default.
- W2551946382 modified "2023-09-25" @default.
- W2551946382 title "Indirect Spectrophotometric Determination of Benzocaine in Pharmaceutical Preparations" @default.
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- W2551946382 doi "https://doi.org/10.33899/rjs.2009.41323" @default.
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