FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2552022278> ?p ?o ?g. }

• W2552022278 abstract "One potential advantage of live attenuated bacterial vaccines is the ability to stimulate responses to antigens which are only expressed during the course of infection. To determine whether the live attenuated cholera vaccine CVD 103-HgR (Vaxchora) results in antibody responses to the in vivo-induced toxin-coregulated pilus antigen TcpA, we measured IgA and IgG responses to Vibrio cholerae O1 El Tor TcpA in a subset of participants in a recently reported experimental challenge study. Participants were challenged with V. cholerae O1 El Tor Inaba N16961 either 10 days or 90 days after receiving the vaccine or a placebo. Neither vaccination nor experimental infection with V. cholerae alone resulted in a robust TcpA IgG or IgA response, but each did elicit a strong response to cholera toxin. However, compared to placebo recipients, vaccinees had a marked increase in IgG TcpA antibodies following the 90-day challenge, suggesting that vaccination with CVD 103-HgR resulted in priming for a subsequent response to TcpA. No such difference between vaccine and placebo recipients was observed for volunteers challenged 10 days after vaccination, indicating that this was insufficient time for vaccine-induced priming of the TcpA response. The priming of the response to TcpA and potentially other antigens expressed in vivo by attenuated V. cholerae may have relevance to the maintenance of immunity in areas where cholera is endemic." @default.
• W2552022278 created "2016-11-30" @default.
• W2552022278 creator A5001360183 @default.
• W2552022278 creator A5001374764 @default.
• W2552022278 creator A5010472783 @default.
• W2552022278 creator A5014624716 @default.
• W2552022278 creator A5044687965 @default.
• W2552022278 creator A5049145301 @default.
• W2552022278 creator A5052410990 @default.
• W2552022278 creator A5065532410 @default.
• W2552022278 creator A5074465314 @default.
• W2552022278 creator A5078198183 @default.
• W2552022278 creator A5084859141 @default.
• W2552022278 creator A5087337307 @default.
• W2552022278 date "2017-01-01" @default.
• W2552022278 modified "2023-10-16" @default.
• W2552022278 title "The Live Attenuated Cholera Vaccine CVD 103-HgR Primes Responses to the Toxin-Coregulated Pilus Antigen TcpA in Subjects Challenged with Wild-Type Vibrio cholerae" @default.
• W2552022278 cites W1801634003 @default.
• W2552022278 cites W1833333324 @default.
• W2552022278 cites W1844213024 @default.
• W2552022278 cites W1892131387 @default.
• W2552022278 cites W1963712790 @default.
• W2552022278 cites W1991373417 @default.
• W2552022278 cites W1994000321 @default.
• W2552022278 cites W1994158536 @default.
• W2552022278 cites W2004693846 @default.
• W2552022278 cites W2006428715 @default.
• W2552022278 cites W2014475594 @default.
• W2552022278 cites W2021918725 @default.
• W2552022278 cites W2029519735 @default.
• W2552022278 cites W2035247219 @default.
• W2552022278 cites W2081883601 @default.
• W2552022278 cites W2091840791 @default.
• W2552022278 cites W2097466208 @default.
• W2552022278 cites W2121456197 @default.
• W2552022278 cites W2132341147 @default.
• W2552022278 cites W2139654401 @default.
• W2552022278 cites W2142941796 @default.
• W2552022278 cites W2156408870 @default.
• W2552022278 cites W2163992829 @default.
• W2552022278 cites W2164263567 @default.
• W2552022278 cites W2309663145 @default.
• W2552022278 cites W4211176329 @default.
• W2552022278 cites W4211207408 @default.
• W2552022278 cites W578603601 @default.
• W2552022278 cites W8336305 @default.
• W2552022278 doi "https://doi.org/10.1128/cvi.00470-16" @default.
• W2552022278 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5216439" @default.
• W2552022278 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27847368" @default.
• W2552022278 hasPublicationYear "2017" @default.
• W2552022278 type Work @default.
• W2552022278 sameAs 2552022278 @default.
• W2552022278 citedByCount "10" @default.
• W2552022278 countsByYear W25520222782017 @default.
• W2552022278 countsByYear W25520222782018 @default.
• W2552022278 countsByYear W25520222782019 @default.
• W2552022278 countsByYear W25520222782021 @default.
• W2552022278 countsByYear W25520222782022 @default.
• W2552022278 countsByYear W25520222782023 @default.
• W2552022278 crossrefType "journal-article" @default.
• W2552022278 hasAuthorship W2552022278A5001360183 @default.
• W2552022278 hasAuthorship W2552022278A5001374764 @default.
• W2552022278 hasAuthorship W2552022278A5010472783 @default.
• W2552022278 hasAuthorship W2552022278A5014624716 @default.
• W2552022278 hasAuthorship W2552022278A5044687965 @default.
• W2552022278 hasAuthorship W2552022278A5049145301 @default.
• W2552022278 hasAuthorship W2552022278A5052410990 @default.
• W2552022278 hasAuthorship W2552022278A5065532410 @default.
• W2552022278 hasAuthorship W2552022278A5074465314 @default.
• W2552022278 hasAuthorship W2552022278A5078198183 @default.
• W2552022278 hasAuthorship W2552022278A5084859141 @default.
• W2552022278 hasAuthorship W2552022278A5087337307 @default.
• W2552022278 hasBestOaLocation W25520222781 @default.
• W2552022278 hasConcept C100701293 @default.
• W2552022278 hasConcept C104317684 @default.
• W2552022278 hasConcept C147483822 @default.
• W2552022278 hasConcept C159047783 @default.
• W2552022278 hasConcept C174832134 @default.
• W2552022278 hasConcept C203014093 @default.
• W2552022278 hasConcept C22070199 @default.
• W2552022278 hasConcept C2777006276 @default.
• W2552022278 hasConcept C2777047711 @default.
• W2552022278 hasConcept C2778643871 @default.
• W2552022278 hasConcept C2779341262 @default.
• W2552022278 hasConcept C2779633232 @default.
• W2552022278 hasConcept C2780722889 @default.
• W2552022278 hasConcept C2780868878 @default.
• W2552022278 hasConcept C523546767 @default.
• W2552022278 hasConcept C54355233 @default.
• W2552022278 hasConcept C55493867 @default.
• W2552022278 hasConcept C59822182 @default.
• W2552022278 hasConcept C60987743 @default.
• W2552022278 hasConcept C81444415 @default.
• W2552022278 hasConcept C86803240 @default.
• W2552022278 hasConcept C8891405 @default.
• W2552022278 hasConcept C89423630 @default.
• W2552022278 hasConceptScore W2552022278C100701293 @default.
• W2552022278 hasConceptScore W2552022278C104317684 @default.
• W2552022278 hasConceptScore W2552022278C147483822 @default.
• W2552022278 hasConceptScore W2552022278C159047783 @default.

• next