FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2552382041> ?p ?o ?g. }

• W2552382041 endingPage "639" @default.
• W2552382041 startingPage "639.1" @default.
• W2552382041 abstract "<h3>Background</h3> Early and accurate detection of erosive joint changes is important when validating and monitoring rheumatoid arthritis (RA). Magnetic resonance imaging (MRI) and ultrasound (US) have shown to be more sensitive than conventional radiography (CR) but have the drawbacks of being expensive (MRI) or difficult to learn (US). In several studies these methods have been compared to multidetector computed tomography (MDCT), which can be considered a reference method for detecting erosions but has several disadvantages, for example the exposure to ionising radiation. With the newly developed cone-beam CT (CBCT) which is dedicated for imaging of the extremities, these disadvantages can be minimized. The radiation dose is low, about 10% of the effective dose of MDCT, comparable to an extra CR exposure. <h3>Objectives</h3> To assess the intra-and interobserver agreement of erosions detected and scored with CBCT. To compare CBCT with CR for assessment of bone erosions in patients with established rheumatoid arthritis. <h3>Methods</h3> 30 patients (23 females, 7 males) with established RA – median disease duration (min-max) 15 (14–15) year – who had CR performed according to the Better AntiRheumatic PharmacOTherapy (BARFOT) study protocol were examined also with extremity CBCT (hands and feet) at the same occasion. Bone erosions were scored twice according to RA MRI score (RAMRIS), on digital images in three planes from the CBCT by two observers. The radiographs were scored by a third observer with Sharp van der Heijde Score (SHS). Disease activity was assessed with disease activity score of 28 joints (DAS28). Remission was defined as DAS28<2.6. Comparisons between groups was performed using Mann-Whitney U test. Correlations were performed with Spearman correlation test and intra class correlation coefficient (ICC) was calculated. <h3>Results</h3> The median age (min-max) was 54 (27–75) and median DAS28 (min-max) 2.25 (0.63–6.49). All 30 patients showed erosions on CBCT and 26 on CR. The correlation between CBCT and CR was 0.77 (p<0.001). Intra-and interobserver reliability for erosions scored by CBCT was excellent for both hands and feet for the two observers (ICC 0.90–0.97).The CBCT erosion scores of 16 patients in remission was median RAMRIS (min-max) 9 (1–67) vs. 21 (2–224), p=0.077 for 11 patients not in remission. The results for CR were for patients in remission median SHS (min-max) 12 (0–97) and those not in remission 40 (6–151), p=0.034. The median (min-max) numbers of eroded joints were 8 (1–40) with CBCT vs. 2 (0–20) with CR for patients in remission and for those not in remission 16 (2–68) with CBCT, vs. 7 (0–34) with CR. There were significantly more eroded joints detected by CBCT, p=0.002. <h3>Conclusions</h3> CBCT is a new low-dose 3 D imaging technique, which has high reproducibility and is more sensitive than CR in detecting erosions. CBCT has a potential to become a useful tool in detecting and follow up of erosions in patients with RA. <h3>Disclosure of Interest</h3> None declared" @default.
• W2552382041 created "2016-11-30" @default.
• W2552382041 creator A5023145884 @default.
• W2552382041 creator A5026988401 @default.
• W2552382041 creator A5040048444 @default.
• W2552382041 creator A5069533961 @default.
• W2552382041 date "2016-06-01" @default.
• W2552382041 modified "2023-09-27" @default.
• W2552382041 title "FRI0549 Cone-Beam Ct, A New Low-Dose 3 D Imaging Technique for Assessment of Bone Erosions in Rheumatoid Arthritis: Reliability Assessment and Comparison with Conventional Radiography" @default.
• W2552382041 doi "https://doi.org/10.1136/annrheumdis-2016-eular.3128" @default.
• W2552382041 hasPublicationYear "2016" @default.
• W2552382041 type Work @default.
• W2552382041 sameAs 2552382041 @default.
• W2552382041 citedByCount "0" @default.
• W2552382041 crossrefType "journal-article" @default.
• W2552382041 hasAuthorship W2552382041A5023145884 @default.
• W2552382041 hasAuthorship W2552382041A5026988401 @default.
• W2552382041 hasAuthorship W2552382041A5040048444 @default.
• W2552382041 hasAuthorship W2552382041A5069533961 @default.
• W2552382041 hasConcept C126322002 @default.
• W2552382041 hasConcept C126838900 @default.
• W2552382041 hasConcept C143409427 @default.
• W2552382041 hasConcept C143753070 @default.
• W2552382041 hasConcept C2777575956 @default.
• W2552382041 hasConcept C2779813781 @default.
• W2552382041 hasConcept C2989005 @default.
• W2552382041 hasConcept C3019088015 @default.
• W2552382041 hasConcept C36454342 @default.
• W2552382041 hasConcept C544519230 @default.
• W2552382041 hasConcept C71924100 @default.
• W2552382041 hasConceptScore W2552382041C126322002 @default.
• W2552382041 hasConceptScore W2552382041C126838900 @default.
• W2552382041 hasConceptScore W2552382041C143409427 @default.
• W2552382041 hasConceptScore W2552382041C143753070 @default.
• W2552382041 hasConceptScore W2552382041C2777575956 @default.
• W2552382041 hasConceptScore W2552382041C2779813781 @default.
• W2552382041 hasConceptScore W2552382041C2989005 @default.
• W2552382041 hasConceptScore W2552382041C3019088015 @default.
• W2552382041 hasConceptScore W2552382041C36454342 @default.
• W2552382041 hasConceptScore W2552382041C544519230 @default.
• W2552382041 hasConceptScore W2552382041C71924100 @default.
• W2552382041 hasIssue "Suppl 2" @default.
• W2552382041 hasLocation W25523820411 @default.
• W2552382041 hasOpenAccess W2552382041 @default.
• W2552382041 hasPrimaryLocation W25523820411 @default.
• W2552382041 hasRelatedWork W1990741171 @default.
• W2552382041 hasRelatedWork W2002876850 @default.
• W2552382041 hasRelatedWork W2028772290 @default.
• W2552382041 hasRelatedWork W2029967375 @default.
• W2552382041 hasRelatedWork W2522299904 @default.
• W2552382041 hasRelatedWork W2801007752 @default.
• W2552382041 hasRelatedWork W2922074762 @default.
• W2552382041 hasRelatedWork W3170934895 @default.
• W2552382041 hasRelatedWork W4242155593 @default.
• W2552382041 hasRelatedWork W4306849910 @default.
• W2552382041 hasVolume "75" @default.
• W2552382041 isParatext "false" @default.
• W2552382041 isRetracted "false" @default.
• W2552382041 magId "2552382041" @default.
• W2552382041 workType "article" @default.