FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2553420848> ?p ?o ?g. }

• W2553420848 abstract "To evaluate the contribution of length diversity in the hemagglutinin-neuraminidase (HN) protein to the pathogenicity, replication and biological characteristics of Newcastle disease virus (NDV), we used reverse genetics to generate a series of recombinant NDVs containing truncated or extended HN proteins based on an infectious clone of genotype VII NDV (SG10 strain). The mean death times and intracerebral pathogenicity indices of these viruses showed that the different length mutations in the HN protein did not alter the virulence of NDV. In vitro studies of recombinant NDVs containing truncated or extended HN proteins revealed that the extension of HN protein increased its hemagglutination titer, receptor-binding ability and impaired its neuraminidase activity, fusogenic activity and replication ability. Furthermore, the hemadsorption, neuraminidase and fusogenic promotion activities at the protein level were consistent with those of viral level. Taken together, our results demonstrate that the HN biological activities affected by the C-terminal extension are associated with NDV replication but not the virulence." @default.
• W2553420848 created "2016-11-30" @default.
• W2553420848 creator A5009824578 @default.
• W2553420848 creator A5012585474 @default.
• W2553420848 creator A5042765146 @default.
• W2553420848 creator A5045860546 @default.
• W2553420848 creator A5079022553 @default.
• W2553420848 date "2016-11-11" @default.
• W2553420848 modified "2023-09-26" @default.
• W2553420848 title "Contribution of HN protein length diversity to Newcastle disease virus virulence, replication and biological activities" @default.
• W2553420848 cites W1203918658 @default.
• W2553420848 cites W1481773415 @default.
• W2553420848 cites W1490002353 @default.
• W2553420848 cites W1533570709 @default.
• W2553420848 cites W1553141706 @default.
• W2553420848 cites W1604712746 @default.
• W2553420848 cites W1954842333 @default.
• W2553420848 cites W1966014847 @default.
• W2553420848 cites W1979362486 @default.
• W2553420848 cites W1980298680 @default.
• W2553420848 cites W1983231883 @default.
• W2553420848 cites W1990574541 @default.
• W2553420848 cites W1992114991 @default.
• W2553420848 cites W1994644330 @default.
• W2553420848 cites W2001888700 @default.
• W2553420848 cites W2003523549 @default.
• W2553420848 cites W2005969892 @default.
• W2553420848 cites W2010015089 @default.
• W2553420848 cites W2017081871 @default.
• W2553420848 cites W2019632525 @default.
• W2553420848 cites W2019969309 @default.
• W2553420848 cites W2020430828 @default.
• W2553420848 cites W2026638402 @default.
• W2553420848 cites W2034814665 @default.
• W2553420848 cites W2036490679 @default.
• W2553420848 cites W2048573278 @default.
• W2553420848 cites W2051263432 @default.
• W2553420848 cites W2053489723 @default.
• W2553420848 cites W2053976944 @default.
• W2553420848 cites W2088377245 @default.
• W2553420848 cites W2092640638 @default.
• W2553420848 cites W2096870824 @default.
• W2553420848 cites W2098194056 @default.
• W2553420848 cites W2102026442 @default.
• W2553420848 cites W2105413808 @default.
• W2553420848 cites W2107872617 @default.
• W2553420848 cites W2111049471 @default.
• W2553420848 cites W2116375762 @default.
• W2553420848 cites W2116407660 @default.
• W2553420848 cites W2118503282 @default.
• W2553420848 cites W2118756391 @default.
• W2553420848 cites W2119705544 @default.
• W2553420848 cites W2127487653 @default.
• W2553420848 cites W2128155533 @default.
• W2553420848 cites W2129946136 @default.
• W2553420848 cites W2133875079 @default.
• W2553420848 cites W2134622732 @default.
• W2553420848 cites W2139183649 @default.
• W2553420848 cites W2149372211 @default.
• W2553420848 cites W2161492108 @default.
• W2553420848 cites W2166375940 @default.
• W2553420848 cites W2169734876 @default.
• W2553420848 cites W2256756668 @default.
• W2553420848 cites W2415981299 @default.
• W2553420848 doi "https://doi.org/10.1038/srep36890" @default.
• W2553420848 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5105081" @default.
• W2553420848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27833149" @default.
• W2553420848 hasPublicationYear "2016" @default.
• W2553420848 type Work @default.
• W2553420848 sameAs 2553420848 @default.
• W2553420848 citedByCount "31" @default.
• W2553420848 countsByYear W25534208482017 @default.
• W2553420848 countsByYear W25534208482018 @default.
• W2553420848 countsByYear W25534208482019 @default.
• W2553420848 countsByYear W25534208482020 @default.
• W2553420848 countsByYear W25534208482021 @default.
• W2553420848 countsByYear W25534208482022 @default.
• W2553420848 countsByYear W25534208482023 @default.
• W2553420848 crossrefType "journal-article" @default.
• W2553420848 hasAuthorship W2553420848A5009824578 @default.
• W2553420848 hasAuthorship W2553420848A5012585474 @default.
• W2553420848 hasAuthorship W2553420848A5042765146 @default.
• W2553420848 hasAuthorship W2553420848A5045860546 @default.
• W2553420848 hasAuthorship W2553420848A5079022553 @default.
• W2553420848 hasBestOaLocation W25534208481 @default.
• W2553420848 hasConcept C104317684 @default.
• W2553420848 hasConcept C134164806 @default.
• W2553420848 hasConcept C140704245 @default.
• W2553420848 hasConcept C159047783 @default.
• W2553420848 hasConcept C2522874641 @default.
• W2553420848 hasConcept C2778116459 @default.
• W2553420848 hasConcept C2780727368 @default.
• W2553420848 hasConcept C2780813555 @default.
• W2553420848 hasConcept C34343649 @default.
• W2553420848 hasConcept C40767141 @default.
• W2553420848 hasConcept C54355233 @default.
• W2553420848 hasConcept C60987743 @default.
• W2553420848 hasConcept C86803240 @default.
• W2553420848 hasConceptScore W2553420848C104317684 @default.
• W2553420848 hasConceptScore W2553420848C134164806 @default.

• next