Matches in SemOpenAlex for { <https://semopenalex.org/work/W2553464592> ?p ?o ?g. }
- W2553464592 endingPage "2260" @default.
- W2553464592 startingPage "2249" @default.
- W2553464592 abstract "// Xianling Zeng 1 , Yafei Zhang 2 , Ting Yue 1 , Taohong Zhang 1 , Junxia Wang 1 , Yan Xue 1 , Ruifang An 1 1 Department of Obstetrics and Gynecology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an Shaanxi 710061, China 2 Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an Shaanxi 710004, China Correspondence to: Ruifang An, email: anruifangxj@163.com Keywords: X-ray repair cross complementing 1, polymorphism, cervical cancer, meta-analysis Received: September 23, 2016 Accepted: November 21, 2016 Published: November 26, 2016 ABSTRACT The present meta-analysis was intended to explore the relationship between the X-ray repair cross complementing 1 (XRCC1) polymorphisms (Arg194Trp, Arg280His and Arg399Gln) and cervical cancer risk. Several electronic databases were searched systematically and bibliographies of relevant papers were identified carefully. Then, a meta-analysis was performed based on eligible studies in various genetic models. Pooled odds ratios (OR) with 95% confidence intervals (95% CI) were employed to evaluate the strength of associations between the XRCC1 polymorphisms and cervical cancer risk. Additionally, heterogeneity analysis and sensitivity analysis were done if necessary. Totally, 11 articles involving 2092 cases and 2803 controls were included. Taken together, there was no obvious association between the Arg194Trp or Arg280His polymorphism and cervical cancer risk. Considering the great heterogeneity, subgroup analysis was done, but the pooled result remained stable. Nevertheless, the association between the Arg399Gln polymorphism and cervical cancer risk showed distinct statistic significance in the allele model, dominant model, homozygous model and heterozygous model. In view of the exiting heterogeneity, we did subgroup analysis stratified by ethnicity, resulting in the fact that the Arg399Gln polymorphism was related to the decreased risk of cervical cancer. The Begg’s test and Egger’s test were used to find no publication bias. To conclude, the current meta-analysis indicated that the XRCC1 Arg399Gln polymorphism decreased the risk of cervical cancer, while the Arg194Trp and Arg280His polymorphisms were not associated with cervical caner risk. Certainly, a well-designed large-scale multicenter study is warranted to confirm the finding." @default.
- W2553464592 created "2016-11-30" @default.
- W2553464592 creator A5003505503 @default.
- W2553464592 creator A5014207196 @default.
- W2553464592 creator A5022634072 @default.
- W2553464592 creator A5035755529 @default.
- W2553464592 creator A5085036291 @default.
- W2553464592 creator A5088938513 @default.
- W2553464592 creator A5089547589 @default.
- W2553464592 date "2016-11-26" @default.
- W2553464592 modified "2023-10-06" @default.
- W2553464592 title "Association between XRCC1 polymorphisms and the risk of cervical cancer: a meta-analysis based on 4895 subjects" @default.
- W2553464592 cites W1908561757 @default.
- W2553464592 cites W1964435302 @default.
- W2553464592 cites W1986444835 @default.
- W2553464592 cites W1991583350 @default.
- W2553464592 cites W2012602505 @default.
- W2553464592 cites W2028399068 @default.
- W2553464592 cites W2032993454 @default.
- W2553464592 cites W2058909001 @default.
- W2553464592 cites W2060423092 @default.
- W2553464592 cites W2083902090 @default.
- W2553464592 cites W2085312575 @default.
- W2553464592 cites W2086590735 @default.
- W2553464592 cites W2094618505 @default.
- W2553464592 cites W2095807096 @default.
- W2553464592 cites W2098910134 @default.
- W2553464592 cites W2101607564 @default.
- W2553464592 cites W2121508150 @default.
- W2553464592 cites W2136840111 @default.
- W2553464592 cites W2144253852 @default.
- W2553464592 cites W2150000105 @default.
- W2553464592 cites W2156579867 @default.
- W2553464592 cites W2157823046 @default.
- W2553464592 cites W2179399924 @default.
- W2553464592 cites W2195038740 @default.
- W2553464592 cites W2197953163 @default.
- W2553464592 cites W2268986409 @default.
- W2553464592 cites W2283028442 @default.
- W2553464592 cites W2283313425 @default.
- W2553464592 cites W2345265653 @default.
- W2553464592 cites W2412720502 @default.
- W2553464592 cites W2414609712 @default.
- W2553464592 cites W2415296535 @default.
- W2553464592 cites W2441675009 @default.
- W2553464592 cites W2483472750 @default.
- W2553464592 doi "https://doi.org/10.18632/oncotarget.13663" @default.
- W2553464592 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5356796" @default.
- W2553464592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27903984" @default.
- W2553464592 hasPublicationYear "2016" @default.
- W2553464592 type Work @default.
- W2553464592 sameAs 2553464592 @default.
- W2553464592 citedByCount "10" @default.
- W2553464592 countsByYear W25534645922017 @default.
- W2553464592 countsByYear W25534645922018 @default.
- W2553464592 countsByYear W25534645922020 @default.
- W2553464592 countsByYear W25534645922021 @default.
- W2553464592 countsByYear W25534645922022 @default.
- W2553464592 countsByYear W25534645922023 @default.
- W2553464592 crossrefType "journal-article" @default.
- W2553464592 hasAuthorship W2553464592A5003505503 @default.
- W2553464592 hasAuthorship W2553464592A5014207196 @default.
- W2553464592 hasAuthorship W2553464592A5022634072 @default.
- W2553464592 hasAuthorship W2553464592A5035755529 @default.
- W2553464592 hasAuthorship W2553464592A5085036291 @default.
- W2553464592 hasAuthorship W2553464592A5088938513 @default.
- W2553464592 hasAuthorship W2553464592A5089547589 @default.
- W2553464592 hasBestOaLocation W25534645921 @default.
- W2553464592 hasConcept C121608353 @default.
- W2553464592 hasConcept C126322002 @default.
- W2553464592 hasConcept C143998085 @default.
- W2553464592 hasConcept C156957248 @default.
- W2553464592 hasConcept C187960798 @default.
- W2553464592 hasConcept C2778220009 @default.
- W2553464592 hasConcept C29456083 @default.
- W2553464592 hasConcept C44249647 @default.
- W2553464592 hasConcept C71924100 @default.
- W2553464592 hasConcept C95190672 @default.
- W2553464592 hasConceptScore W2553464592C121608353 @default.
- W2553464592 hasConceptScore W2553464592C126322002 @default.
- W2553464592 hasConceptScore W2553464592C143998085 @default.
- W2553464592 hasConceptScore W2553464592C156957248 @default.
- W2553464592 hasConceptScore W2553464592C187960798 @default.
- W2553464592 hasConceptScore W2553464592C2778220009 @default.
- W2553464592 hasConceptScore W2553464592C29456083 @default.
- W2553464592 hasConceptScore W2553464592C44249647 @default.
- W2553464592 hasConceptScore W2553464592C71924100 @default.
- W2553464592 hasConceptScore W2553464592C95190672 @default.
- W2553464592 hasIssue "2" @default.
- W2553464592 hasLocation W25534645921 @default.
- W2553464592 hasLocation W25534645922 @default.
- W2553464592 hasLocation W25534645923 @default.
- W2553464592 hasLocation W25534645924 @default.
- W2553464592 hasOpenAccess W2553464592 @default.
- W2553464592 hasPrimaryLocation W25534645921 @default.
- W2553464592 hasRelatedWork W2074274808 @default.
- W2553464592 hasRelatedWork W2159313323 @default.
- W2553464592 hasRelatedWork W2286371484 @default.