Matches in SemOpenAlex for { <https://semopenalex.org/work/W2553522629> ?p ?o ?g. }
- W2553522629 endingPage "69" @default.
- W2553522629 startingPage "62" @default.
- W2553522629 abstract "Sustained anabolic-androgenic steroid (AAS) use has adverse behavioral consequences, including aggression, violence and impulsivity. Candidate mechanisms include disruptions of brain networks with high concentrations of androgen receptors and critically involved in emotional and cognitive regulation. Here, we tested the effects of AAS on resting-state functional brain connectivity in the largest sample of AAS-users to date. We collected resting-state functional magnetic resonance imaging (fMRI) data from 151 males engaged in heavy resistance strength training. 50 users tested positive for AAS based on the testosterone to epitestosterone (T/E) ratio and doping substances in urine. 16 previous users and 59 controls tested negative. We estimated brain network nodes and their time-series using ICA and dual regression and defined connectivity matrices as the between-node partial correlations. In line with the emotional and behavioral consequences of AAS, current users exhibited reduced functional connectivity between key nodes involved in emotional and cognitive regulation, in particular reduced connectivity between the amygdala and default-mode network (DMN) and between the dorsal attention network (DAN) and a frontal node encompassing the superior and inferior frontal gyri (SFG/IFG) and the anterior cingulate cortex (ACC), with further reductions as a function of dependency, lifetime exposure, and cycle state (on/off)." @default.
- W2553522629 created "2016-11-30" @default.
- W2553522629 creator A5002668347 @default.
- W2553522629 creator A5003414597 @default.
- W2553522629 creator A5006168982 @default.
- W2553522629 creator A5023842321 @default.
- W2553522629 creator A5025645521 @default.
- W2553522629 date "2017-01-01" @default.
- W2553522629 modified "2023-10-16" @default.
- W2553522629 title "Brain connectivity aberrations in anabolic-androgenic steroid users" @default.
- W2553522629 cites W1512463247 @default.
- W2553522629 cites W1698476268 @default.
- W2553522629 cites W1905519752 @default.
- W2553522629 cites W1929409154 @default.
- W2553522629 cites W1968166735 @default.
- W2553522629 cites W1969100427 @default.
- W2553522629 cites W1974342654 @default.
- W2553522629 cites W1979086245 @default.
- W2553522629 cites W1986311333 @default.
- W2553522629 cites W1987094115 @default.
- W2553522629 cites W1987521153 @default.
- W2553522629 cites W1994710765 @default.
- W2553522629 cites W1994955799 @default.
- W2553522629 cites W2001789423 @default.
- W2553522629 cites W2002882833 @default.
- W2553522629 cites W2003550381 @default.
- W2553522629 cites W2004293194 @default.
- W2553522629 cites W2004739445 @default.
- W2553522629 cites W2006096283 @default.
- W2553522629 cites W2011478741 @default.
- W2553522629 cites W2012312341 @default.
- W2553522629 cites W2020044743 @default.
- W2553522629 cites W2032534791 @default.
- W2553522629 cites W2033702782 @default.
- W2553522629 cites W2034855022 @default.
- W2553522629 cites W2039866939 @default.
- W2553522629 cites W2041325253 @default.
- W2553522629 cites W2046024437 @default.
- W2553522629 cites W2047726099 @default.
- W2553522629 cites W2050581082 @default.
- W2553522629 cites W2050834126 @default.
- W2553522629 cites W2052615191 @default.
- W2553522629 cites W2058857405 @default.
- W2553522629 cites W2065768713 @default.
- W2553522629 cites W2067963436 @default.
- W2553522629 cites W2072522618 @default.
- W2553522629 cites W2072646528 @default.
- W2553522629 cites W2072895554 @default.
- W2553522629 cites W2082047348 @default.
- W2553522629 cites W2082573808 @default.
- W2553522629 cites W2083937756 @default.
- W2553522629 cites W2083956595 @default.
- W2553522629 cites W2084978329 @default.
- W2553522629 cites W2086792459 @default.
- W2553522629 cites W2093072166 @default.
- W2553522629 cites W2094439724 @default.
- W2553522629 cites W2104016179 @default.
- W2553522629 cites W2104178671 @default.
- W2553522629 cites W2109301184 @default.
- W2553522629 cites W2114046308 @default.
- W2553522629 cites W2117621792 @default.
- W2553522629 cites W2117693696 @default.
- W2553522629 cites W2120938638 @default.
- W2553522629 cites W2121174368 @default.
- W2553522629 cites W2125823313 @default.
- W2553522629 cites W2126391114 @default.
- W2553522629 cites W2127339438 @default.
- W2553522629 cites W2136435696 @default.
- W2553522629 cites W2138905229 @default.
- W2553522629 cites W2146352944 @default.
- W2553522629 cites W2148726987 @default.
- W2553522629 cites W2157446241 @default.
- W2553522629 cites W2165408259 @default.
- W2553522629 cites W2171719429 @default.
- W2553522629 cites W2173994997 @default.
- W2553522629 cites W2209172268 @default.
- W2553522629 cites W2211147350 @default.
- W2553522629 cites W2253171309 @default.
- W2553522629 cites W2296159117 @default.
- W2553522629 cites W2306925547 @default.
- W2553522629 cites W2339872010 @default.
- W2553522629 cites W2425812215 @default.
- W2553522629 cites W2474840999 @default.
- W2553522629 cites W2553557322 @default.
- W2553522629 cites W9265140 @default.
- W2553522629 doi "https://doi.org/10.1016/j.nicl.2016.11.014" @default.
- W2553522629 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5133655" @default.
- W2553522629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27942448" @default.
- W2553522629 hasPublicationYear "2017" @default.
- W2553522629 type Work @default.
- W2553522629 sameAs 2553522629 @default.
- W2553522629 citedByCount "52" @default.
- W2553522629 countsByYear W25535226292017 @default.
- W2553522629 countsByYear W25535226292018 @default.
- W2553522629 countsByYear W25535226292019 @default.
- W2553522629 countsByYear W25535226292020 @default.
- W2553522629 countsByYear W25535226292021 @default.
- W2553522629 countsByYear W25535226292022 @default.