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- W2553528265 abstract "Background: Lung clearance index (LCI), a measure of ventilation inhomogeneity, is increasingly studied in non-cystic fibrosis bronchiectasis (NCFB). However, its interest in assessing interventions in this disease remains unclear. In addition, chest physiotherapy is frequently advocated in patients with NCFB despite a lack of objective benefit using standard lung function tests. Objectives: To assess the short-term effects of autogenic drainage (AD) in NCFB adults using standard lung function tests and LCI. Methods: LCI, spirometry and body plethysmography tests were performed before 30-min AD in stable NCFB patients. After the AD session, the tests were repeated in the same order. Dry and wet expectorated sputum were quantified during the AD session and correlated with % of change between post and pre measurements (Δ, in %). Results: 24 patients were studied (18 F, median (range) age: 65y (21 – 81). LCI significantly improved with AD (mean ± SD: 10.88 ± 2.62 vs 10.53 ± 2.35, p Conclusion: In NCFB adults, AD has a significant short-term impact on ventilation inhomogeneity. LCI change may be the result of the maximal mobilized lung volume recruited and the amount of cleared mucus secretion." @default.
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- W2553528265 date "2016-09-01" @default.
- W2553528265 modified "2023-09-24" @default.
- W2553528265 title "Short-term effect of autogenic drainage on ventilation inhomogeneity in adults with stable non-cystic fibrosis bronchiectasis" @default.
- W2553528265 doi "https://doi.org/10.1183/13993003.congress-2016.pa1366" @default.
- W2553528265 hasPublicationYear "2016" @default.
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