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• W2553561306 endingPage "83" @default.
• W2553561306 startingPage "83" @default.
• W2553561306 abstract "Insufficient hepatic O2 in animal and human studies has been shown to elicit a hepatorenal reflex in response to increased hepatic adenosine, resulting in stimulation of renal as well as muscle sympathetic nerve activity and activating the renin angiotensin system. Low hepatic ATP, hyperuricemia, and hepatic lipid accumulation reported in metabolic syndrome (MetS) patients may reflect insufficient hepatic O2 delivery, potentially accounting for the sympathetic overdrive associated with MetS. This theoretical concept is supported by experimental results in animals fed a high fructose diet to induce MetS. Hepatic fructose metabolism rapidly consumes ATP resulting in increased adenosine production and hyperuricemia as well as elevated renin release and sympathetic activity. This review makes the case for the hepatorenal reflex causing sympathetic overdrive and metabolic syndrome in response to exaggerated splanchnic oxygen consumption from excessive eating. This is strongly reinforced by the fact that MetS is cured in a matter of days in a significant percentage of patients by diet, bariatric surgery, or endoluminal sleeve, all of which would decrease splanchnic oxygen demand by limiting nutrient contact with the mucosa and reducing the nutrient load due to the loss of appetite or dietary restriction." @default.
• W2553561306 created "2016-11-30" @default.
• W2553561306 creator A5072072474 @default.
• W2553561306 date "2016-01-01" @default.
• W2553561306 modified "2023-10-16" @default.
• W2553561306 title "Metabolic syndrome and the hepatorenal reflex" @default.
• W2553561306 cites W100094386 @default.
• W2553561306 cites W12841686 @default.
• W2553561306 cites W130756297 @default.
• W2553561306 cites W1512475175 @default.
• W2553561306 cites W1572399582 @default.
• W2553561306 cites W1579491283 @default.
• W2553561306 cites W1648277606 @default.
• W2553561306 cites W1687707398 @default.
• W2553561306 cites W1706470322 @default.
• W2553561306 cites W1794816071 @default.
• W2553561306 cites W1864860694 @default.
• W2553561306 cites W1880249534 @default.
• W2553561306 cites W1916676407 @default.
• W2553561306 cites W1929731436 @default.
• W2553561306 cites W1952359548 @default.
• W2553561306 cites W1954463628 @default.
• W2553561306 cites W1962648987 @default.
• W2553561306 cites W1964548443 @default.
• W2553561306 cites W1965147638 @default.
• W2553561306 cites W1965357229 @default.
• W2553561306 cites W1965921539 @default.
• W2553561306 cites W1965943690 @default.
• W2553561306 cites W1966048075 @default.
• W2553561306 cites W1966579300 @default.
• W2553561306 cites W1968272089 @default.
• W2553561306 cites W1969182257 @default.
• W2553561306 cites W1969852310 @default.
• W2553561306 cites W1970318048 @default.
• W2553561306 cites W1971122483 @default.
• W2553561306 cites W1971173619 @default.
• W2553561306 cites W1971453640 @default.
• W2553561306 cites W1972630718 @default.
• W2553561306 cites W1973021910 @default.
• W2553561306 cites W1973226951 @default.
• W2553561306 cites W1973512499 @default.
• W2553561306 cites W1973757701 @default.
• W2553561306 cites W1973835317 @default.
• W2553561306 cites W1975495812 @default.
• W2553561306 cites W1975860147 @default.
• W2553561306 cites W1975912944 @default.
• W2553561306 cites W1976544514 @default.
• W2553561306 cites W1977040679 @default.
• W2553561306 cites W1977356230 @default.
• W2553561306 cites W1977819123 @default.
• W2553561306 cites W1978579229 @default.
• W2553561306 cites W1978756416 @default.
• W2553561306 cites W1979249143 @default.
• W2553561306 cites W1979595233 @default.
• W2553561306 cites W1980033214 @default.
• W2553561306 cites W1980567021 @default.
• W2553561306 cites W1981423956 @default.
• W2553561306 cites W1981915199 @default.
• W2553561306 cites W1982371057 @default.
• W2553561306 cites W1983842819 @default.
• W2553561306 cites W1984223131 @default.
• W2553561306 cites W1986885124 @default.
• W2553561306 cites W1987282451 @default.
• W2553561306 cites W1987593352 @default.
• W2553561306 cites W1987602959 @default.
• W2553561306 cites W1987914240 @default.
• W2553561306 cites W1989036422 @default.
• W2553561306 cites W1989400130 @default.
• W2553561306 cites W1989847128 @default.
• W2553561306 cites W1990097540 @default.
• W2553561306 cites W1990393024 @default.
• W2553561306 cites W1990948355 @default.
• W2553561306 cites W1991585987 @default.
• W2553561306 cites W1994130476 @default.
• W2553561306 cites W1995915021 @default.
• W2553561306 cites W1997443520 @default.
• W2553561306 cites W1998140042 @default.
• W2553561306 cites W2001657480 @default.
• W2553561306 cites W2001971051 @default.
• W2553561306 cites W2002213597 @default.
• W2553561306 cites W2002619263 @default.
• W2553561306 cites W2002736272 @default.
• W2553561306 cites W2004985023 @default.
• W2553561306 cites W2004987231 @default.
• W2553561306 cites W2006972130 @default.
• W2553561306 cites W2007608045 @default.
• W2553561306 cites W2008308392 @default.
• W2553561306 cites W2008350418 @default.
• W2553561306 cites W2008351784 @default.
• W2553561306 cites W2009067533 @default.
• W2553561306 cites W2009227031 @default.
• W2553561306 cites W2009510103 @default.
• W2553561306 cites W2011354705 @default.
• W2553561306 cites W2013232839 @default.
• W2553561306 cites W2013687731 @default.
• W2553561306 cites W2015453495 @default.
• W2553561306 cites W2017508606 @default.
• W2553561306 cites W2017558893 @default.

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